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HTS to identify compounds that affect the blood-brain barrier permeability in vitro
Assay data:419 Active, 1260 Tested
SummaryCompounds, Active
Discovery of Small Molecules to Inhibit Human Cytomegalovirus Nuclear Egress
Assay data:281 Active, 189401 Tested
Primary qHTS Assay for Inhibitors of Recombinant Selenoprotein Glutathione Peroxidase 4 (GPX4)
Assay data:258 Active, 16 Activity ≤ 1 µM, 11046 Tested
SummaryCompounds, ActiveCompounds, activity ≤ 1 µMRelated BioAssays by DepositorRelated BioAssays by Target
Primary qHTS Assay for Inhibitors of Recombinant Selenoprotein Glutathione Peroxidase 1 (GPX1)
Assay data:186 Active, 9 Activity ≤ 1 µM, 11353 Tested
qHTS to identify inhibitors of the New Delhi Metallo-beta-lactamase (NDM): assay validation screen against the NCATS LOPAC Collection
Assay data:10 Active, 7 Activity ≤ 1 µM, 1248 Tested
SummaryCompounds, ActiveCompounds, activity ≤ 1 µMPubMed CitationRelated BioAssays by DepositorRelated BioAssays by Target
Fluorescence-based screening to identify small molecule inhibitors of Plasmodium falciparum apicoplast DNA polymerase (Pf-apPOL).
Assay data:523 Active, 206263 Tested
SummaryCompounds, ActivePubMed Citation
Primary Screen for Target Class Profiling of Small Molecule Inhibitors of Methyltransferases
Assay data:968 Active, 24930 Tested
SummaryCompounds, ActivePubMed CitationRelated BioAssays by DepositorRelated BioAssays by Target
Primary qHTS assay for inhibitors of alpha-synuclein gene (SNCA) expression
Assay data:237 Active, 1947 Activity ≤ 1 µM, 141380 Tested
GF-AFC viability counterscreen for inhibitors of alpha-synuclein gene (SNCA) expression
Assay data:177 Active, 2 Activity ≤ 1 nM, 481 Activity ≤ 1 µM, 146379 Tested
SummaryCompounds, ActiveCompounds, activity ≤ 1 µMPubMed CitationRelated BioAssays by Depositor
Primary qHTS assay for inhibitors of Glutamate pyruvate transaminase 2 (GPT2)
Assay data:249 Active, 449 Activity ≤ 1 µM, 100803 Tested
Validation qHTS for agonist of cAMP-regulated guanine nucleotide exchange factor 4 (EPAC2)
Assay data:41 Active, 124 Activity ≤ 1 µM, 15613 Tested
Validation qHTS for antagonist of cAMP-regulated guanine nucleotide exchange factor 4 (EPAC2)
Assay data:265 Active, 171 Activity ≤ 1 µM, 15637 Tested
Validation qHTS for agonist of cAMP-regulated guanine nucleotide exchange factor 3 (EPAC1)
Assay data:160 Active, 22 Activity ≤ 1 µM, 15634 Tested
Validation qHTS for antagonist of cAMP-regulated guanine nucleotide exchange factor 3 (EPAC1)
Assay data:115 Active, 91 Activity ≤ 1 µM, 15634 Tested
Primary qHTS assay for inhibitors of the protease papain
Assay data:54 Active, 27 Activity ≤ 1 µM, 1272 Tested
Rescue cell viability in cybrid cells with a genetic mutation in complex 1 of the mitochondria
Assay data:128 Active, 5056 Tested
Primary qHTS for small molecule stabilizers of the endoplasmic reticulum resident proteome: Secreted ER Calcium Modulated Protein (SERCaMP) assay
Assay data:41 Active, 8 Activity ≤ 1 nM, 357 Activity ≤ 1 µM, 11292 Tested
Validation qHTS for Identification of Calcium Integrin Binding protein 1 (CIB1) Competitor
Assay data:10 Active, 7 Activity ≤ 1 µM, 1277 Tested
Primary qHTS for inhibitors of La Crosse Virus (LACV) - induced cell death in SH-SY5Y cells
Assay data:30 Active, 282 Activity ≤ 1 µM, 3830 Tested
SummaryCompounds, ActiveCompounds, activity ≤ 1 µM
Cell-based high throughput primary assay to identify activators of GPR151
Assay data:6756 Active, 646675 Tested
SummaryCompounds, ActiveRelated BioAssays by DepositorRelated BioAssays by Target
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