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Inhibition of IgE/Ag-mediated immediate hypersensitivity reaction in BALB/c mouse assessed as change in the level of skin extravasation at 0 to 4 mg/kg, po administered 1 hr prior to Ag challenge
Assay data:1 Tested
SummaryPubMed Citation
EZH2/PRC2 methyltransferase inhibitors Measured in Biochemical System Using Plate Reader - 2125-01_Inhibitor_SinglePoint_HTS_Activity
Assay data:201 Active, 57246 Tested
SummaryCompounds, ActiveRelated BioAssays by Target
NSD2 Inhibitors Measured in Biochemical System Using Plate Reader - 2115-01_Inhibitor_SinglePoint_HTS_Activity
Assay data:28 Active, 44352 Tested
Fluorescence Cell-Based Primary HTS to Identify Reactive Oxygen Species Inducers in Cancer Cells Measured in Cell-Based System Using Plate Reader and Imaging Combination - 2044-01_Activator_SinglePoint_HTS_Activity
Assay data:901 Active, 46019 Tested
SummaryCompounds, Active
Luminescence Cell-Based Primary HTS to Identify Re-Activators of the P53 Mutant Pathway Measured in Cell-Based System Using Plate Reader - 2071-01_Activator_SinglePoint_HTS_Activity
Assay data:414 Active, 27679 Tested
SMM c-myc Measured in Biochemical System Using Small Molecule MicroArray - 2081-01_Other_SinglePoint_HTS_Activity
Assay data:257 Active, 16958 Tested
NF-KappaB Measured in Biochemical System Using Small Molecule MicroArray - 2080-01_Other_SinglePoint_HTS_Activity
Assay data:218 Active, 16958 Tested
SMM STAT-3 Measured in Biochemical System Using Small Molecule MicroArray - 2076-01_Other_SinglePoint_HTS_Activity_Set2
Assay data:37 Active, 16958 Tested
SMM ID4 Measured in Biochemical System Using Small Molecule MicroArray - 2128-01_Other_SinglePoint_HTS_Activity
Assay data:362 Active, 31373 Tested
mutant P53 Measured in Biochemical System Using Small Molecule MicroArray - 2077-01_Other_SinglePoint_HTS_Activity
Assay data:76 Active, 16958 Tested
Development of IDH1/2 inhibitors (CTD2project) Measured in Biochemical System Using Plate Reader - 2107-01_Inhibitor_SinglePoint_HTS_Activity
Assay data:123 Active, 70208 Tested
SummaryCompounds, ActivePubMed CitationRelated BioAssays by Target
Fluorescence Cell-Based Primary HTS to Measure Inhibition of Y box Binding Protein 1 Expression
Assay data:113 Active, 30318 Tested
Hepatoprotective activity against H2O2-induced hepatotoxicity in Wistar rat hepatocytes assessed as reduction in glutamic pyruvate transaminase release after 1 hr relative to control
Assay data:3 Active, 9 Tested
SummaryCompounds, ActivePubMed Citation
Luminescence Homogenous Primary HTS to Identify Inhibitors of STK33 Activity
Assay data:119 Active, 26840 Tested
Luminescence Cell-Based Primary HTS to Identify Inhibitors of the Sonic Hedgehog Signaling Pathway
Assay data:458 Active, 21753 Tested
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