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Displacement of [3H]NMS from recombinant human M3 receptor expressed in CHO-K1 cells after 16 hrs by SPA method
Assay data:68 Active, 52 Activity ≤ 1 nM, 68 Activity ≤ 1 µM, 68 Tested
SummaryCompounds, ActiveCompounds, activity ≤ 1 µMPubMed CitationRelated BioAssays by Target
Antagonist potency at M3 receptor in Dunkin Hartley guinea pig trachea assessed as inhibition of methacholine-induced airway smooth muscle contraction after 1 hr by organ-bath technique
Assay data:47 Active, 41 Activity ≤ 1 nM, 47 Activity ≤ 1 µM, 47 Tested
SummaryCompounds, ActiveCompounds, activity ≤ 1 µMPubMed Citation
Displacement of [3H]NMS from recombinant human M2 receptor expressed in CHO-K1 cells after 16 hrs
Assay data:3 Active, 3 Activity ≤ 1 nM, 3 Activity ≤ 1 µM, 3 Tested
Displacement of [3H]NMS from recombinant human M3 receptor expressed in CHO-K1 cells after 16 hrs
Assay data:85 Active, 63 Activity ≤ 1 nM, 85 Activity ≤ 1 µM, 85 Tested
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