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p53 small molecule agonists, cell-based qHTS assay
Assay data:87 Active, 5 Activity ≤ 1 nM, 180 Activity ≤ 1 µM, 9667 Tested
SummaryCompounds, ActiveCompounds, activity ≤ 1 µMRelated BioAssays by DepositorRelated BioAssays by Same Project
Compound was evaluated for inhibition of human PTGS2 in an in vitro cell free assay measured by fluorescence spectroscopy
Assay data:79 Active, 12 Activity ≤ 1 µM, 1183 Tested
SummaryCompounds, ActiveCompounds, activity ≤ 1 µMPubMed CitationRelated BioAssays by Target
Inhibition of human recombinant CA9
Assay data:9 Active, 9 Activity ≤ 1 µM, 9 Tested
Inhibition of recombinant human COX-2 using arachidonic acid as substrate preincubated with compound for 5 mins followed by substrate addition and measured after 2 mins by fluorescence spectrum analysis
Assay data:3 Active, 1 Activity ≤ 1 µM, 3 Tested
Inhibition of sheep COX-2 by Cayman colorimetric analysis
Assay data:3 Active, 3 Activity ≤ 1 µM, 3 Tested
Inhibition of COX-2 (unknown origin) using arachidonic acid as substrate preincubated for 5 mins followed by substrate addition and measured after 1 hr by spectrophotometer based analysis
Assay data:6 Active, 6 Activity ≤ 1 µM, 6 Tested
Inhibition of ovine COX-2 colorimetric enzyme immunoassay
Assay data:13 Active, 13 Activity ≤ 1 µM, 13 Tested
Inhibition of 15-LOX (unknown origin)
Assay data:23 Active, 1 Activity ≤ 1 µM, 24 Tested
Inhibition of human recombinant COX-2
Assay data:23 Active, 23 Activity ≤ 1 µM, 23 Tested
Inhibition of COX-2 (unknown origin) using arachidonic acid as substrate preincubated for 5 mins followed by substrate addition and measured after 1 hr by absorbance based analysis
Assay data:4 Active, 4 Activity ≤ 1 µM, 4 Tested
Inhibition of recombinant human COX-2 by enzyme immunoassay
Inhibition of COX-2 (unknown origin) using arachidonic acid as substrate incubated for 5 to 10 mins by fluorometric analysis
Assay data:7 Active, 5 Activity ≤ 1 µM, 7 Tested
Inhibition of human COX-2 using arachidonic acid as substrate preincubated for 10 mins followed by substrate addition and measured after 2 mins by ELISA
Assay data:99 Active, 98 Activity ≤ 1 µM, 100 Tested
Inhibition of recombinant human COX-2 by colorimetric enzyme immunoassay
Inhibition of COX-2 (unknown origin) using arachidonic acid as substrate incubated for 1 min by absorbance based analysis
Assay data:12 Active, 12 Activity ≤ 1 µM, 12 Tested
Inhibition of COX1 (unknown origin)
Assay data:7 Active, 7 Activity ≤ 1 µM, 9 Tested
Inhibition of COX-2 (unknown origin) at 0.5 uM by colorimetric assay
Assay data:4 Active, 2 Activity ≤ 1 µM, 5 Tested
Inhibition of COX-2 (unknown origin) by EIA kit method
Inhibition of human COX-2
Assay data:5 Active, 5 Activity ≤ 1 µM, 5 Tested
Inhibition of COX-2 (unknown origin)
Assay data:9 Active, 8 Activity ≤ 1 µM, 11 Tested
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