BioAssays, activity concentration at/below 1 uM for PubChem Compound ( - PubChem BioAssay - NCBI

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Items: 16

Select item 19291241.

Antiproliferative activity against human MCF7 cells assessed as inhibition of cell proliferation measured after 48 hrs by MTT assay

Source:: ChEMBL

Assay data:16 Active, 12 Activity ≤ 1 µM, 16 Tested

AID:: 1929124

Summary Compounds, Active Compounds, activity ≤ 1 µM PubMed Citation

Select item 19291232.

Antiproliferative activity against human KB cells assessed as inhibition of cell proliferation measured after 48 hrs by MTT assay

Source:: ChEMBL

Assay data:16 Active, 13 Activity ≤ 1 µM, 16 Tested

AID:: 1929123

Summary Compounds, Active Compounds, activity ≤ 1 µM PubMed Citation

Select item 19291223.

Antiproliferative activity against human MDA-MB-231 cells assessed as inhibition of cell proliferation measured after 48 hrs by MTT assay

Source:: ChEMBL

Assay data:47 Active, 46 Activity ≤ 1 µM, 47 Tested

AID:: 1929122

Summary Compounds, Active Compounds, activity ≤ 1 µM PubMed Citation

Select item 17590784.

Inhibition of recombinant rat MAGL by LC-MS analysis

Source:: ChEMBL

Protein Target:: Monoglyceride lipase

Assay data:2 Active, 2 Activity ≤ 1 µM, 2 Tested

AID:: 1759078

Summary Compounds, Active Compounds, activity ≤ 1 µM PubMed Citation Related BioAssays by Target

Select item 15975235.

Binding affinity to recombinant human N-terminal His-tagged Nur77 LBD (367 to 598 residues) expressed in Escherichia coli BL21(DE3) incubated for 30 secs by fluorescence quenching assay

Source:: ChEMBL

Protein Target:: Nuclear receptor subfamily 4 group A member 1

Assay data:15 Active, 9 Activity ≤ 1 µM, 25 Tested

AID:: 1597523

Summary Compounds, Active Compounds, activity ≤ 1 µM PubMed Citation Related BioAssays by Target

Select item 15086066.

Confirmatory qHTS for activators (rescue) of SARS-CoV-2 Cytopathic Effect (CPE)

Source:: National Center for Advancing Translational Sciences (NCATS)

Assay data:124 Active, 30 Activity ≤ 1 µM, 365 Tested

AID:: 1508606

Summary Compounds, Active Compounds, activity ≤ 1 µM PubMed Citation Related BioAssays by Depositor

Select item 14541617.

Cytotoxic activity against human HepG2 cells incubated for 48 hrs by MTT assay

Source:: ChEMBL

Assay data:27 Active, 16 Activity ≤ 1 µM, 27 Tested

AID:: 1454161

Summary Compounds, Active Compounds, activity ≤ 1 µM PubMed Citation

Select item 14541608.

Cytotoxic activity against human HeLa cells incubated for 48 hrs by MTT assay

Source:: ChEMBL

Assay data:26 Active, 13 Activity ≤ 1 µM, 27 Tested

AID:: 1454160

Summary Compounds, Active Compounds, activity ≤ 1 µM PubMed Citation

Select item 14541599.

Cytotoxic activity against human SGC7901 cells incubated for 48 hrs by MTT assay

Source:: ChEMBL

Assay data:26 Active, 18 Activity ≤ 1 µM, 27 Tested

AID:: 1454159

Summary Compounds, Active Compounds, activity ≤ 1 µM PubMed Citation

Select item 73373710.

Cytotoxicity against human MCF7 cells assessed as growth inhibition after 72 hrs by MTT assay

Source:: ChEMBL

Assay data:1 Active, 1 Activity ≤ 1 µM, 28 Tested

AID:: 733737

Summary Compounds, Active Compounds, activity ≤ 1 µM PubMed Citation

Select item 56685311.

Cytotoxicity against human MCF7 cells after 48 hrs by MTT assay

Source:: ChEMBL

Assay data:6 Active, 1 Activity ≤ 1 µM, 9 Tested

AID:: 566853

Summary Compounds, Active Compounds, activity ≤ 1 µM PubMed Citation

Select item 56677912.

Cytotoxicity against human HL60 cells after 48 hrs by MTT assay

Source:: ChEMBL

Assay data:9 Active, 6 Activity ≤ 1 µM, 9 Tested

AID:: 566779

Summary Compounds, Active Compounds, activity ≤ 1 µM PubMed Citation

Select item 48931113.

Antitumor activity against mouse SW1 cells

Source:: ChEMBL

Assay data:2 Active, 2 Activity ≤ 1 µM, 2 Tested

AID:: 489311

Summary Compounds, Active Compounds, activity ≤ 1 µM PubMed Citation

Select item 44970414.

NOVARTIS: Inhibition of Plasmodium falciparum W2 (drug-resistant) proliferation in erythrocyte-based infection assay

Source:: ChEMBL

Assay data:4616 Active, 9 Activity ≤ 1 nM, 3714 Activity ≤ 1 µM, 5614 Tested

AID:: 449704

Summary Compounds, Active Compounds, activity ≤ 1 µM PubMed Citation

Select item 28623215.

Antiprotozoal activity against Giardia intestinalis IMSS:0696:1 trophozoites after 48 hrs

Source:: ChEMBL

Assay data:3 Active, 2 Activity ≤ 1 µM, 7 Tested

AID:: 286232

Summary Compounds, Active Compounds, activity ≤ 1 µM PubMed Citation

Select item 9082416.

Inhibitory activity against LPS-stimulated 1L-1beta release by cultured human monocytes

Source:: ChEMBL

Assay data:5 Active, 5 Activity ≤ 1 µM, 5 Tested

AID:: 90824

Summary Compounds, Active Compounds, activity ≤ 1 µM PubMed Citation

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BioActivity

Active Compounds (16)
BioAssays with compounds reported as biologically active
Activity (IC50, etc) ≤ 1 nM (1)
BioAssays with the active concentration of tested reagents less than 1 nanomolar
Activity (IC50, etc) ≤ 1 µM (16)
BioAssays with the active concentration of tested reagents less than 1 micromolar

Experiment Type

Confirmatory (16)
Low-throughput BioAssays where the activity outcome is based on a dose-response relationship with multiple tested concentrations

Depositor Category

Literature Extraction (14)
BioAssays extracted from the literature
NIH MLP (1)
BioAssays deposited by the NIH Molecular Libraries Program
Other (1)
BioAssays deposited by other experimentalists

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