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p53 small molecule agonists, cell-based qHTS assay
Assay data:87 Active, 5 Activity ≤ 1 nM, 180 Activity ≤ 1 µM, 9667 Tested
SummaryCompounds, ActiveCompounds, activity ≤ 1 µMRelated BioAssays by DepositorRelated BioAssays by Same Project
Nuclear factor erythroid 2-related factor 2/antioxidant responsive element (Nrf2/ARE) small molecule agonists: luciferase reporter gene qHTS assay in human keratinocytes
Assay data:1099 Active, 1 Activity ≤ 1 nM, 143 Activity ≤ 1 µM, 9667 Tested
Cytochrome P450 Family 2 Subfamily D Member 6 (CYP2D6) small molecule antagonists: luciferase reporter qHTS assay
Assay data:2225 Active, 268 Activity ≤ 1 µM, 9667 Tested
SummaryCompounds, ActiveCompounds, activity ≤ 1 µMPubMed CitationRelated BioAssays by DepositorRelated BioAssays by Target
Human pregnane X receptor (PXR) small molecule agonists, qHTS assay
Assay data:2218 Active, 1 Activity ≤ 1 nM, 106 Activity ≤ 1 µM, 9667 Tested
SummaryCompounds, ActiveCompounds, activity ≤ 1 µMRelated BioAssays by DepositorRelated BioAssays by Same ProjectRelated BioAssays by Target
Caspase-3/7 induction in CHO-K1 cells by small molecules, qHTS assay
Assay data:127 Active, 25 Activity ≤ 1 µM, 9667 Tested
Caspase-3/7 induction in CHO-K1 cells by small molecules, qHTS cell viability counter screen
Assay data:1380 Active, 82 Activity ≤ 1 µM, 9667 Tested
qHTS assay to identify small molecule agonists of the TGF-beta/Smad signaling pathway
Assay data:13 Active, 24 Activity ≤ 1 µM, 9667 Tested
qHTS assay to identify small molecule antagonists of the progesterone receptor (PR) signaling pathway
Assay data:724 Active, 1 Activity ≤ 1 nM, 121 Activity ≤ 1 µM, 9667 Tested
qHTS assay to identify small molecule antagonists of the estrogen related receptor (ERR) signaling pathway from Tox21 library: Summary
Assay data:807 Active, 131 Activity ≤ 1 µM, 9667 Tested
qHTS assay to identify small molecule antagonists of the estrogen related receptor signaling pathway with the pleiotropic PPARgamma coactivator (PGC) from Tox21 10K library: Summary
Assay data:462 Active, 149 Activity ≤ 1 µM, 9667 Tested
qHTS assay to identify small molecule antagonists of the sonic hedgehog signaling (Shh) pathway: Summary
Assay data:1156 Active, 2 Activity ≤ 1 nM, 322 Activity ≤ 1 µM, 9667 Tested
qHTS assay to identify small molecule antagonists of the estrogen receptor beta (ER-beta) signaling pathway - cell viability counter screen
Assay data:562 Active, 40 Activity ≤ 1 µM, 9667 Tested
qHTS assay to identify small molecule agonists of the estrogen receptor beta (ER-beta) signaling pathway - cell viability counter screen
Assay data:1136 Active, 121 Activity ≤ 1 µM, 9667 Tested
qHTS assay to identify small molecule antagonists of the sonic hedgehog signaling (Shh) pathway
Assay data:1356 Active, 2 Activity ≤ 1 nM, 487 Activity ≤ 1 µM, 9667 Tested
qHTS assay to identify small molecule antagonists of the sonic hedgehog signaling (Shh) pathway - cell viability counter screen
Assay data:714 Active, 57 Activity ≤ 1 µM, 9667 Tested
qHTS assay to identify small molecule agonists of the sonic hedgehog signaling (Shh) pathway - cell viability counter screen
Assay data:750 Active, 58 Activity ≤ 1 µM, 9667 Tested
qHTS assay to identify small molecule antagonists of the androgen receptor (AR) signaling pathway using the MDA cell line in the presence of 0.5 nM R1881: Summary
Assay data:1108 Active, 2 Activity ≤ 1 nM, 246 Activity ≤ 1 µM, 9667 Tested
qHTS assay to identify small molecule antagonists of the estrogen receptor alpha (ER-alpha) signaling pathway using the BG1 cell line in the presence of 0.1 nM 17-beta-estradiol
Assay data:727 Active, 1 Activity ≤ 1 nM, 196 Activity ≤ 1 µM, 9667 Tested
SummaryCompounds, ActiveCompounds, activity ≤ 1 µMPubMed CitationRelated BioAssays by DepositorRelated BioAssays by Same ProjectRelated BioAssays by Target
qHTS assay to identify small molecule antagonists of the androgen receptor (AR) signaling pathway using the MDA cell line in the presence of 0.5 nM R1881
Assay data:1453 Active, 4 Activity ≤ 1 nM, 292 Activity ≤ 1 µM, 9667 Tested
qHTS assay to identify small molecule agonists of H2AX: Summary
Assay data:519 Active, 48 Activity ≤ 1 µM, 9667 Tested
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