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Inhibition of ALK6 (unknown origin)
Assay data:1 Active, 1 Activity ≤ 1 µM, 1 Tested
SummaryCompounds, ActiveCompounds, activity ≤ 1 µMPubMed CitationRelated BioAssays by Target
Inhibition of ALK3 (unknown origin)
Inhibition of ALK2 (unknown origin)
Inhibition of BMPR2 (unknown origin)
Quantitative High-Throughput drug screen in 47 multiple myeloma cell lines against the NCATS MIPE library collection: KMS21BM_JCRB cell viability assay
Assay data:650 Active, 358 Activity ≤ 1 nM, 751 Activity ≤ 1 µM, 1912 Tested
SummaryCompounds, ActiveCompounds, activity ≤ 1 µMPubMed CitationRelated BioAssays by Depositor
Quantitative High-Throughput drug screen in 47 multiple myeloma cell lines against the NCATS MIPE library collection: JIM1_ECACC cell viability assay
Assay data:457 Active, 27 Activity ≤ 1 nM, 619 Activity ≤ 1 µM, 1912 Tested
Quantitative High-Throughput drug screen in 47 multiple myeloma cell lines against the NCATS MIPE library collection: Karpas417_ECACC cell viability assay
Assay data:508 Active, 171 Activity ≤ 1 nM, 712 Activity ≤ 1 µM, 1912 Tested
Quantitative High-Throughput drug screen in 47 multiple myeloma cell lines against the NCATS MIPE library collection: AMO1_DSMZ cell viability assay
Assay data:746 Active, 20 Activity ≤ 1 nM, 455 Activity ≤ 1 µM, 1912 Tested
Binding affinity to AMPK (unknown origin)
SummaryCompounds, ActiveCompounds, activity ≤ 1 µMPubMed Citation
Kinase Assay from US Patent US9040694: "Compounds and methods useful for directing stem cell differentiation"
Assay data:6 Active, 6 Activity ≤ 1 µM, 6 Tested
SummaryCompounds, ActiveCompounds, activity ≤ 1 µMRelated BioAssays by Target
in vitro Kinase Assay from Article 10.1021/cb9002865: "In vivo structure-activity relationship study of dorsomorphin analogues identifies selective VEGF and BMP inhibitors."
Assay data:7 Active, 1 Activity ≤ 1 nM, 7 Activity ≤ 1 µM, 7 Tested
SummaryCompounds, ActiveCompounds, activity ≤ 1 µMPubMed CitationRelated BioAssays by DepositorRelated BioAssays by Target
Antimitotic activity against human A2780 cells by ATP lite luminescence assay
Assay data:12 Active, 6 Activity ≤ 1 µM, 12 Tested
Inhibition of human KDR in presence of (33P)gamma ATP
Inhibition of human AMPK in presence of (33P)gamma ATP
Identifying Small Molecule Inhibitors of Pancreatic Cancer Stem Cells (Panc1, Spheroid)
Assay data:67 Active, 5 Activity ≤ 1 nM, 143 Activity ≤ 1 µM, 464 Tested
SummaryCompounds, ActiveCompounds, activity ≤ 1 µMRelated BioAssays by DepositorRelated BioAssays by Same Project
Reversible competitive inhibition of Sprague-Dawley rat liver AMPK using 33P-ATP as substrate after 30 mins
Inhibition of ALK6 (unknown origin) by radioisotopic assay
Assay data:1 Active, 1 Activity ≤ 1 µM, 2 Tested
Inhibition of Yes1 (unknown origin) assessed as kinase-dependent enzymatic production of ADP from ATP using coupled luminescence-based reaction by ADP-Glo kinase assay
Assay data:10 Active, 1 Activity ≤ 1 nM, 9 Activity ≤ 1 µM, 10 Tested
Inhibition of Yes1 (unknown origin) by [gamma-33P]-ATP radiolabeled enzyme activity assay
Assay data:10 Active, 2 Activity ≤ 1 nM, 10 Activity ≤ 1 µM, 10 Tested
Inhibition of ALK1 (unknown origin)
Assay data:11 Active, 11 Activity ≤ 1 µM, 11 Tested
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