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Cytochrome P450 Family 1 Subfamily A Member 2 (CYP1A2) small molecule antagonists: luciferase reporter qHTS assay
Assay data:2934 Active, 132 Activity ≤ 1 µM, 9667 Tested
SummaryCompounds, ActiveCompounds, activity ≤ 1 µMPubMed CitationRelated BioAssays by DepositorRelated BioAssays by Target
CCRIS carcinogenicity studies
Assay data:1139 Active, 1767 Tested
SummaryCompounds, Active
qHTS assay to identify small molecule agonists of the RXR signaling pathway
Assay data:178 Active, 159 Activity ≤ 1 µM, 9667 Tested
SummaryCompounds, ActiveCompounds, activity ≤ 1 µMPubMed CitationRelated BioAssays by DepositorRelated BioAssays by Same ProjectRelated BioAssays by Target
Induction of changes in hyphae ultrastructures in Phytophthora cactorum at 0.052 ug/ml by transmission electron microscopy
Assay data:1 Active, 1 Tested
Induction of changes in hyphae ultrastructures in Phytophthora cactorum assessed as plasmalemma invagination at 0.052 ug/ml by transmission electron microscopy
Induction of changes in hyphae ultrastructures in Phytophthora cactorum assessed as cell wall thickening at 0.052 ug/ml by transmission electron microscopy
Induction of changes in hyphae ultrastructures in Phytophthora cactorum assessed as membranes obscuring at 0.052 ug/ml by transmission electron microscopy
Induction of changes in hyphae ultrastructures in Phytophthora cactorum assessed as mitochondria level changes at 0.052 ug/ml by transmission electron microscopy
Induction of changes in hyphae ultrastructures in Phytophthora cactorum assessed as endoplasmic reticulum structure changes at 0.052 ug/ml by transmission electron microscopy
Acaricidal activity against Dermatophagoides pteronyssinus assessed as mortality at 0.8 to 1.2 ug/cm2 after 24 to 72 hr by fabric disk assay relative to untreated control
SummaryCompounds, ActivePubMed Citation
qHTS assay to identify small molecule agonists of the estrogen receptor alpha (ER-alpha) signaling pathway using the BG1 cell line
Assay data:1084 Active, 8 Activity ≤ 1 nM, 330 Activity ≤ 1 µM, 10486 Tested
SummaryCompounds, ActiveCompounds, activity ≤ 1 µMPubMed CitationRelated BioAssays by Target
qHTS assay for small molecule agonists of the antioxidant response element (ARE) signaling pathway
Assay data:583 Active, 1 Activity ≤ 1 nM, 42 Activity ≤ 1 µM, 2810 Tested
uHTS Fluorescent Assay Using Nedd8 Protein Substrate for Identification of Inhibitors of Sentrin-Specific Protease 8 (SENP8)
Assay data:2342 Active, 364168 Tested
SummaryCompounds, ActivePubMed CitationRelated BioAssays by DepositorRelated BioAssays by Same ProjectRelated BioAssays by Target
Luminescence Microorganism Primary HTS to Identify Inhibitors of the SUMOylation Pathway Using a Temperature Sensitive Growth Reversal Mutant Mot1-301
Assay data:3324 Active, 318770 Tested
SummaryCompounds, ActivePubMed CitationRelated BioAssays by DepositorRelated BioAssays by Same Project
DSSTox (CPDBAS) Carcinogenic Potency Database Summary Rat Bioassay Results
Assay data:586 Active, 1240 Tested
DSSTox (CPDBAS) Carcinogenic Potency Database Summary MultiCellCall Results
Assay data:582 Active, 1152 Tested
DSSTox (CPDBAS) Carcinogenic Potency Database Summary Mouse Bioassay Results
Assay data:445 Active, 1007 Tested
DSSTox (CPDBAS) Carcinogenic Potency Database Summary SingleCellCall Results
Assay data:806 Active, 1547 Tested
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