BioAssays, Active for PubChem Compound (Select 6918837) - PubChem BioAssay - NCBI

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Select item 19233441.

Inhibition of HDAC11 (unknown origin)

Source:: ChEMBL

Protein Target:: Histone deacetylase 11

Assay data:3 Active, 3 Activity ≤ 1 µM, 4 Tested

AID:: 1923344

Summary Compounds, Active Compounds, activity ≤ 1 µM PubMed Citation Related BioAssays by Target

Select item 19233432.

Inhibition of HDAC10 (unknown origin)

Source:: ChEMBL

Protein Target:: Polyamine deacetylase HDAC10

Assay data:4 Active, 3 Activity ≤ 1 µM, 4 Tested

AID:: 1923343

Summary Compounds, Active Compounds, activity ≤ 1 µM PubMed Citation Related BioAssays by Target

Select item 19233423.

Inhibition of HDAC9 (unknown origin)

Source:: ChEMBL

Protein Target:: Histone deacetylase 9

Assay data:3 Active, 3 Activity ≤ 1 µM, 5 Tested

AID:: 1923342

Summary Compounds, Active Compounds, activity ≤ 1 µM PubMed Citation Related BioAssays by Target

Select item 19233414.

Inhibition of HDAC8 (unknown origin)

Source:: ChEMBL

Protein Target:: Histone deacetylase 8

Assay data:5 Active, 4 Activity ≤ 1 µM, 5 Tested

AID:: 1923341

Summary Compounds, Active Compounds, activity ≤ 1 µM PubMed Citation Related BioAssays by Target

Select item 19233405.

Inhibition of HDAC7 (unknown origin)

Source:: ChEMBL

Protein Target:: Histone deacetylase 7

Assay data:4 Active, 2 Activity ≤ 1 µM, 5 Tested

AID:: 1923340

Summary Compounds, Active Compounds, activity ≤ 1 µM PubMed Citation Related BioAssays by Target

Select item 19233396.

Inhibition of HDAC6 (unknown origin)

Source:: ChEMBL

Protein Target:: Histone deacetylase 6

Assay data:7 Active, 7 Activity ≤ 1 µM, 7 Tested

AID:: 1923339

Summary Compounds, Active Compounds, activity ≤ 1 µM PubMed Citation Related BioAssays by Target

Select item 19233387.

Inhibition of HDAC5 (unknown origin)

Source:: ChEMBL

Protein Target:: Histone deacetylase 5

Assay data:4 Active, 3 Activity ≤ 1 µM, 5 Tested

AID:: 1923338

Summary Compounds, Active Compounds, activity ≤ 1 µM PubMed Citation Related BioAssays by Target

Select item 19233378.

Inhibition of HDAC4 (unknown origin)

Source:: ChEMBL

Protein Target:: Histone deacetylase 4

Assay data:3 Active, 1 Activity ≤ 1 µM, 5 Tested

AID:: 1923337

Summary Compounds, Active Compounds, activity ≤ 1 µM PubMed Citation Related BioAssays by Target

Select item 19233369.

Inhibition of HDAC3 (unknown origin)

Source:: ChEMBL

Protein Target:: Histone deacetylase 3

Assay data:5 Active, 5 Activity ≤ 1 µM, 5 Tested

AID:: 1923336

Summary Compounds, Active Compounds, activity ≤ 1 µM PubMed Citation Related BioAssays by Target

Select item 192333510.

Inhibition of HDAC2 (unknown origin)

Source:: ChEMBL

Protein Target:: Histone deacetylase 2

Assay data:5 Active, 5 Activity ≤ 1 µM, 6 Tested

AID:: 1923335

Summary Compounds, Active Compounds, activity ≤ 1 µM PubMed Citation Related BioAssays by Target

Select item 192333411.

Inhibition of HDAC1 (unknown origin)

Source:: ChEMBL

Protein Target:: Histone deacetylase 1

Assay data:6 Active, 5 Activity ≤ 1 µM, 6 Tested

AID:: 1923334

Summary Compounds, Active Compounds, activity ≤ 1 µM PubMed Citation Related BioAssays by Target

Select item 188246712.

Inhibition of HDAC8 (unknown origin)

Source:: ChEMBL

Protein Target:: Histone deacetylase 8

Assay data:5 Active, 3 Activity ≤ 1 µM, 5 Tested

AID:: 1882467

Summary Compounds, Active Compounds, activity ≤ 1 µM PubMed Citation Related BioAssays by Target

Select item 188246613.

Inhibition of HDAC3 (unknown origin)

Source:: ChEMBL

Protein Target:: Histone deacetylase 3

Assay data:4 Active, 3 Activity ≤ 1 µM, 5 Tested

AID:: 1882466

Summary Compounds, Active Compounds, activity ≤ 1 µM PubMed Citation Related BioAssays by Target

Select item 188246214.

Inhibition of HDAC6 (unknown origin)

Source:: ChEMBL

Protein Target:: Histone deacetylase 6

Assay data:7 Active, 7 Activity ≤ 1 µM, 7 Tested

AID:: 1882462

Summary Compounds, Active Compounds, activity ≤ 1 µM PubMed Citation Related BioAssays by Target

Select item 188245615.

Inhibition of HDAC1 (unknown origin)

Source:: ChEMBL

Protein Target:: Histone deacetylase 1

Assay data:6 Active, 3 Activity ≤ 1 µM, 8 Tested

AID:: 1882456

Summary Compounds, Active Compounds, activity ≤ 1 µM PubMed Citation Related BioAssays by Target

Select item 188226016.

Inhibition of HDAC6 (unknown origin)

Source:: ChEMBL

Protein Target:: Histone deacetylase 6

Assay data:3 Active, 3 Activity ≤ 1 µM, 3 Tested

AID:: 1882260

Summary Compounds, Active Compounds, activity ≤ 1 µM PubMed Citation Related BioAssays by Target

Select item 184601817.

Anticancer activity against human MED-MEB-8A cells assessed as reduction in cell viability incubated for 72 hrs by CCK assay

Source:: ChEMBL

Assay data:1 Active, 1 Activity ≤ 1 µM, 1 Tested

AID:: 1846018

Summary Compounds, Active Compounds, activity ≤ 1 µM PubMed Citation

Select item 184601718.

Anticancer activity against human UW426 cells assessed as reduction in cell viability incubated for 72 hrs by CCK assay

Source:: ChEMBL

Assay data:1 Active, 1 Activity ≤ 1 µM, 1 Tested

AID:: 1846017

Summary Compounds, Active Compounds, activity ≤ 1 µM PubMed Citation

Select item 184601619.

Anticancer activity against human UW228 cells assessed as reduction in cell viability incubated for 72 hrs by CCK assay

Source:: ChEMBL

Assay data:1 Active, 1 Activity ≤ 1 µM, 1 Tested

AID:: 1846016

Summary Compounds, Active Compounds, activity ≤ 1 µM PubMed Citation

Select item 184591420.

Inhibition of HIV-1 latency in human CD4+ve Th cells infected NL4.3-Luc virus assessed as p24 expression level incubated for 48 hrs by v450 dye based flow cytometry

Source:: ChEMBL

Assay data:3 Active, 3 Activity ≤ 1 µM, 3 Tested

AID:: 1845914

Summary Compounds, Active Compounds, activity ≤ 1 µM PubMed Citation

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Proteins (20)
BioAssays with protein sequences specified as targets

BioActivity

Active Compounds (399)
BioAssays with compounds reported as biologically active
Activity (IC50, etc) ≤ 1 nM (55)
BioAssays with the active concentration of tested reagents less than 1 nanomolar
Activity (IC50, etc) ≤ 1 µM (259)
BioAssays with the active concentration of tested reagents less than 1 micromolar

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Confirmatory (332)
Low-throughput BioAssays where the activity outcome is based on a dose-response relationship with multiple tested concentrations
Primary Screening (4)
Primary high-throughput BioAssays where the activity outcome is based on percentage inhibition from a single dose

Assay Project (2)
BioAssays organized into assay projects based on linkage to Summary assays. Click an project below to retrieve the bioassay list for the project. Click 'All Assay Projects' to retrieve all assay projects represented by Summary assays.

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Literature Extraction (304)
BioAssays extracted from the literature
NIH MLP (11)
BioAssays deposited by the NIH Molecular Libraries Program
Other (84)
BioAssays deposited by other experimentalists

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