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Compound was evaluated for inhibition of human PTGS1 in an in vitro cell free assay measured by time-resolved fluorescence resonance energy transfer method
Assay data:96 Active, 35 Activity ≤ 1 µM, 927 Tested
SummaryCompounds, ActiveCompounds, activity ≤ 1 µMPubMed CitationRelated BioAssays by Target
Quantitative High-Throughput drug screen in 47 multiple myeloma cell lines against the NCATS MIPE library collection: KMS21BM_JCRB cell viability assay
Assay data:650 Active, 358 Activity ≤ 1 nM, 751 Activity ≤ 1 µM, 1912 Tested
SummaryCompounds, ActiveCompounds, activity ≤ 1 µMPubMed CitationRelated BioAssays by Depositor
Quantitative High-Throughput drug screen in 47 multiple myeloma cell lines against the NCATS MIPE library collection: Karpas417_ECACC cell viability assay
Assay data:508 Active, 171 Activity ≤ 1 nM, 712 Activity ≤ 1 µM, 1912 Tested
Antibacterial activity against Bacillus subtilis assessed as inhibition of protein synthesis at 100 mg/L after 50 mins by [35S]-methionine incorporation assay
Assay data:2 Active, 2 Tested
SummaryCompounds, ActivePubMed Citation
Antibacterial activity against Bacillus subtilis assessed as inhibition of plasma membrane lipids synthesis at 100 mg/L after 50 mins by [3H]-sodium acetate incorporation assay
Antibacterial activity against Bacillus subtilis assessed as inhibition of peptidoglycan synthesis at 100 mg/L after 50 mins by [3H]-N-acetylglucosamine incorporation assay
Antibacterial activity against Bacillus subtilis assessed as inhibition of RNA synthesis at 100 mg/L after 50 mins by [3H]-uridine incorporation assay
Antibacterial activity against Bacillus subtilis assessed as inhibition of DNA synthesis at 100 mg/L after 50 mins by [3H]thymidine incorporation assay
Inhibitor identification of human QSOX1 enzyme: high-throughput screening using HyperBlu(TM) assay
Assay data:979 Active, 1265 Tested
SummaryCompounds, ActiveRelated BioAssays by Depositor
Antimicrobial activity against Salmonella typhimurium ATCC 19430 incubated for 18 hrs by agar dilution method
Assay data:5 Active, 28 Tested
CCRIS carcinogenicity studies
Assay data:1139 Active, 1767 Tested
SummaryCompounds, Active
GENE-TOX mutagenicity studies
Assay data:1995 Active, 3214 Tested
CCRIS mutagenicity studies
Assay data:4929 Active, 8266 Tested
The chemical genetic matrix (CGM) dataset as reported in Wildenhain et al. (2015) Prediction of Synergism from Chemical-Genetic Interactions by Machine Learning. Cell Systems Volume 1, Issue 6, p383-395
Assay data:2021 Active, 5518 Tested
SummaryCompounds, ActiveRelated BioAssays by Same Project
A screen for compounds that inhibit growth of Escherichia coli
Assay data:702 Active, 329176 Tested
Antibacterial activity against wild type Enterobacter aerogenes ATCC 13048 assessed as growth inhibition after 18 hrs by CLSI broth dilution method
Assay data:3 Active, 1 Activity ≤ 1 µM, 23 Tested
SummaryCompounds, ActiveCompounds, activity ≤ 1 µMPubMed Citation
Fluorescence-based biochemical high throughput primary assay to identify inhibitors of phospholipase C isozymes (PLC-gamma1).
Assay data:3123 Active, 370276 Tested
SummaryCompounds, ActivePubMed CitationRelated BioAssays by DepositorRelated BioAssays by Same ProjectRelated BioAssays by Target
Counterscreen for RECBCD inhibitors: absorbance-based high throughput cell-based assay to identify inhibitors of AddAB recombination protein complex
Assay data:401 Active, 892 Tested
Counterscreen for inhibitors of RecBCD: Absorbance-based cell-based high throughput assay to identify inhibitors of bacterial viability
Assay data:263 Active, 892 Tested
SummaryCompounds, ActivePubMed CitationRelated BioAssays by DepositorRelated BioAssays by Same Project
Absorbance-based bacterial cell-based high throughput confirmation assay to identify inhibitors of RecBCD
Assay data:399 Active, 892 Tested
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