BioAssays, Active for PubChem Compound (Select 3811) - PubChem BioAssay - NCBI

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Items: 14

Select item 18477721.

Inhibition of HDAC in Sprague-Dawley rat hepatocytes using Fluor de Lys as substrate incubated for 15 mins by fluorometric assay

Source:: ChEMBL

Assay data:2 Active, 2 Activity ≤ 1 µM, 2 Tested

AID:: 1847772

Summary Compounds, Active Compounds, activity ≤ 1 µM PubMed Citation

Select item 12593892.

HIV1_TAR : FRET assay measuring displacement of FAM and TAMRA-labeled Tat peptide from HIV-1 TAR RNA.

Source:: Center for Chemical Genomics, University of Michigan

Assay data:618 Active, 103146 Tested

AID:: 1259389

Summary Compounds, Active

Select item 3730833.

Antiproliferative activity against human HeLa cells after 4 hrs by WST-1 assay

Source:: ChEMBL

Assay data:15 Active, 1 Activity ≤ 1 µM, 33 Tested

AID:: 373083

Summary Compounds, Active Compounds, activity ≤ 1 µM PubMed Citation

Select item 3730734.

Inhibition of HDAC from human HeLa cells

Source:: ChEMBL

Protein Targets:: Histone deacetylase 1; ...
Total:: 11

Assay data:23 Active, 23 Activity ≤ 1 µM, 24 Tested

AID:: 373073

Summary Compounds, Active Compounds, activity ≤ 1 µM PubMed Citation Related BioAssays by Target

Select item 2425995.

Inhibitory concentration against human histone deacetylase (HDAC) from HeLa cells with substrate 5a

Source:: ChEMBL

Protein Targets:: Histone deacetylase 1; ...
Total:: 11

Assay data:1 Active, 1 Tested

AID:: 242599

Summary Compounds, Active PubMed Citation Related BioAssays by Target

Select item 2425596.

Inhibitory concentration against rat liver histone deacetylase (HDAC) with substrate 3a

Source:: ChEMBL

Protein Targets:: Histone deacetylase; ...
Total:: 7

Assay data:2 Active, 2 Activity ≤ 1 µM, 2 Tested

AID:: 242559

Summary Compounds, Active Compounds, activity ≤ 1 µM PubMed Citation Related BioAssays by Target

Select item 2423827.

Inhibitory concentration against rat liver histone deacetylase (HDAC) with substrate 5a

Source:: ChEMBL

Protein Targets:: Histone deacetylase; ...
Total:: 7

Assay data:1 Active, 1 Activity ≤ 1 µM, 1 Tested

AID:: 242382

Summary Compounds, Active Compounds, activity ≤ 1 µM PubMed Citation Related BioAssays by Target

Select item 2423818.

Inhibitory concentration against rat liver histone deacetylase (HDAC) with substrate 3b

Source:: ChEMBL

Protein Targets:: Histone deacetylase; ...
Total:: 7

Assay data:1 Active, 1 Activity ≤ 1 µM, 1 Tested

AID:: 242381

Summary Compounds, Active Compounds, activity ≤ 1 µM PubMed Citation Related BioAssays by Target

Select item 906959.

Inhibition of maize Histone deacetylase 2 (HD-2) activity

Source:: ChEMBL

Protein Target:: HD2 type histone deacetylase HDA106

Assay data:11 Active, 10 Activity ≤ 1 µM, 11 Tested

AID:: 90695

Summary Compounds, Active Compounds, activity ≤ 1 µM PubMed Citation Related BioAssays by Target

Select item 9068710.

Inhibitory concentration against maize Histone deacetylase 2

Source:: ChEMBL

Protein Target:: HD2 type histone deacetylase HDA106

Assay data:24 Active, 22 Activity ≤ 1 µM, 26 Tested

AID:: 90687

Summary Compounds, Active Compounds, activity ≤ 1 µM PubMed Citation Related BioAssays by Target

Select item 9052211.

Inhibitory concentration against rat liver Histone deacetylase

Source:: ChEMBL

Protein Targets:: Histone deacetylase; ...
Total:: 7

Assay data:25 Active, 22 Activity ≤ 1 µM, 26 Tested

AID:: 90522

Summary Compounds, Active Compounds, activity ≤ 1 µM PubMed Citation Related BioAssays by Target

Select item 9052112.

Inhibitory activity against histone deacetylase (HDAC)

Source:: ChEMBL

Protein Targets:: Histone deacetylase; ...
Total:: 7

Assay data:3 Active, 3 Activity ≤ 1 µM, 4 Tested

AID:: 90521

Summary Compounds, Active Compounds, activity ≤ 1 µM PubMed Citation Related BioAssays by Target

Select item 9035413.

Inhibitory concentration against human histone deacetylase (HDAC)

Source:: ChEMBL

Protein Targets:: Histone deacetylase 1; ...
Total:: 11

Assay data:4 Active, 4 Activity ≤ 1 µM, 5 Tested

AID:: 90354

Summary Compounds, Active Compounds, activity ≤ 1 µM PubMed Citation Related BioAssays by Target

Select item 9035114.

Concentration required to inhibit human Histone deacetylase (HDAC) enzyme by 50%

Source:: ChEMBL

Protein Targets:: Histone deacetylase 1; ...
Total:: 11

Assay data:20 Active, 19 Activity ≤ 1 µM, 23 Tested

AID:: 90351

Summary Compounds, Active Compounds, activity ≤ 1 µM PubMed Citation Related BioAssays by Target

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Target

Proteins (7)
BioAssays with protein sequences specified as targets

BioActivity

Active Compounds (14)
BioAssays with compounds reported as biologically active
Activity (IC50, etc) ≤ 1 µM (12)
BioAssays with the active concentration of tested reagents less than 1 micromolar

Experiment Type

Confirmatory (13)
Low-throughput BioAssays where the activity outcome is based on a dose-response relationship with multiple tested concentrations
Primary Screening (1)
Primary high-throughput BioAssays where the activity outcome is based on percentage inhibition from a single dose

Depositor Category

Literature Extraction (13)
BioAssays extracted from the literature
Other (1)
BioAssays deposited by other experimentalists

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BioAssays, Active for PubChem Compound (Select 3811) (14)
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