BioAssays, Active for PubChem Compound (Select 2764) - PubChem BioAssay - NCBI

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Select item 19557491.

Antibacterial activity against Staphylococcus aureus ATCC 25923

Source:: ChEMBL

Assay data:4 Active, 1 Activity ≤ 1 µM, 4 Tested

AID:: 1955749

Summary Compounds, Active Compounds, activity ≤ 1 µM PubMed Citation

Select item 19412182.

Antimicrobial activity against methicillin-resistant Staphylococcus aureus N315 by two fold broth dilution method

Source:: ChEMBL

Assay data:9 Active, 3 Activity ≤ 1 nM, 9 Activity ≤ 1 µM, 9 Tested

AID:: 1941218

Summary Compounds, Active Compounds, activity ≤ 1 µM PubMed Citation

Select item 19296543.

Antibacterial activity against Salmonella ATCC 12022 assessed as inhibition of bacterial growth by standard broth microdilution method

Source:: ChEMBL

Assay data:17 Active, 2 Activity ≤ 1 µM, 20 Tested

AID:: 1929654

Summary Compounds, Active Compounds, activity ≤ 1 µM PubMed Citation

Select item 19296524.

Antibacterial activity against Escherichia coli ATCC 25922 assessed as inhibition of bacterial growth by standard broth microdilution method

Source:: ChEMBL

Assay data:17 Active, 1 Activity ≤ 1 µM, 20 Tested

AID:: 1929652

Summary Compounds, Active Compounds, activity ≤ 1 µM PubMed Citation

Select item 19263695.

Antibacterial activity against Vibrio parahaemolyticus assessed as inhibition of bacterial growth incubated for 24 hrs by microbroth dilution method

Source:: ChEMBL

Assay data:7 Active, 3 Activity ≤ 1 µM, 14 Tested

AID:: 1926369

Summary Compounds, Active Compounds, activity ≤ 1 µM PubMed Citation

Select item 19263686.

Antibacterial activity against Bacillus subtilis assessed as inhibition of bacterial growth incubated for 24 hrs by microbroth dilution method

Source:: ChEMBL

Assay data:8 Active, 5 Activity ≤ 1 µM, 14 Tested

AID:: 1926368

Summary Compounds, Active Compounds, activity ≤ 1 µM PubMed Citation

Select item 19263677.

Antibacterial activity against Mycobacterium phlei assessed as inhibition of bacterial growth incubated for 24 hrs by microbroth dilution method

Source:: ChEMBL

Assay data:4 Active, 2 Activity ≤ 1 µM, 14 Tested

AID:: 1926367

Summary Compounds, Active Compounds, activity ≤ 1 µM PubMed Citation

Select item 19263668.

Antibacterial activity against Proteus sp. assessed as inhibition of bacterial growth incubated for 24 hrs by microbroth dilution method

Source:: ChEMBL

Assay data:2 Active, 2 Activity ≤ 1 µM, 14 Tested

AID:: 1926366

Summary Compounds, Active Compounds, activity ≤ 1 µM PubMed Citation

Select item 19263659.

Antibacterial activity against Bacillus cereus assessed as inhibition of bacterial growth incubated for 24 hrs by microbroth dilution method

Source:: ChEMBL

Assay data:5 Active, 1 Activity ≤ 1 µM, 14 Tested

AID:: 1926365

Summary Compounds, Active Compounds, activity ≤ 1 µM PubMed Citation

Select item 191930810.

Enzyme Inhibition Assay from US Patent US11590142: "Oxazolidinone antibiotic compounds and process of preparation"

Source:: BindingDB

Protein Targets:: DNA gyrase inhibitor; ...
Total:: 1

Assay data:7 Active, 7 Activity ≤ 1 µM, 7 Tested

AID:: 1919308

Summary Compounds, Active Compounds, activity ≤ 1 µM Related BioAssays by Depositor

Select item 191729911.

Inhibition of Escherichia coli topoisomerase 4 mediated relaxation of supercoiled pHOT1 DNA at expense of ATP hydrolysis by ethidium bromide staining based agarose gel electrophoresis

Source:: ChEMBL

Assay data:3 Active, 3 Tested

AID:: 1917299

Summary Compounds, Active PubMed Citation

Select item 191729812.

Inhibition of Escherichia coli DNA gyrase supercoiling activity using topoisomerase II treated decatenated kDNA as substrate incubated for 15 to 30 mins by agarose gel electrophoresis analysis

Source:: ChEMBL

Protein Targets:: DNA gyrase subunit A; ...
Total:: 2

Assay data:3 Active, 1 Activity ≤ 1 µM, 3 Tested

AID:: 1917298

Summary Compounds, Active Compounds, activity ≤ 1 µM PubMed Citation Related BioAssays by Target

Select item 191729713.

Antibacterial activity against methicillin-resistant Staphylococcus aureus AUMC 261 assessed as zone of inhibition by cup-plate agar diffusion method

Source:: ChEMBL

Assay data:7 Active, 4 Activity ≤ 1 µM, 7 Tested

AID:: 1917297

Summary Compounds, Active Compounds, activity ≤ 1 µM PubMed Citation

Select item 191729614.

Antibacterial activity against Staphylococcus aureus ATCC6538 assessed as zone of inhibition by cup-plate agar diffusion method

Source:: ChEMBL

Assay data:5 Active, 21 Tested

AID:: 1917296

Summary Compounds, Active PubMed Citation

Select item 191729515.

Antibacterial activity against Pseudomonas aeruginosa ATCC27853 assessed as zone of inhibition by cup-plate agar diffusion method

Source:: ChEMBL

Assay data:4 Active, 1 Activity ≤ 1 µM, 21 Tested

AID:: 1917295

Summary Compounds, Active Compounds, activity ≤ 1 µM PubMed Citation

Select item 191729416.

Antibacterial activity against Klebsiella pneumoniae ATCC10031 assessed as zone of inhibition by cup-plate agar diffusion method

Source:: ChEMBL

Assay data:14 Active, 21 Tested

AID:: 1917294

Summary Compounds, Active PubMed Citation

Select item 191729317.

Antibacterial activity against Escherichia coli ATCC6538 assessed as zone of inhibition by cup-plate agar diffusion method

Source:: ChEMBL

Assay data:17 Active, 2 Activity ≤ 1 µM, 21 Tested

AID:: 1917293

Summary Compounds, Active Compounds, activity ≤ 1 µM PubMed Citation

Select item 191659218.

Antitubercular activity against Mycobacterium tuberculosis H37Rv ATCC 27294 assessed as bacterial growth inhibition measured after 5 days by MABA method

Source:: ChEMBL

Assay data:3 Active, 1 Activity ≤ 1 µM, 37 Tested

AID:: 1916592

Summary Compounds, Active Compounds, activity ≤ 1 µM PubMed Citation

Select item 195615319.

Antibacterial activity against methicillin resistant Staphylococcus aureus assessed as reduction in bacterial growth at 8 times MIC measured at 24 hrs by time kill assay

Source:: ChEMBL

Assay data:4 Active, 4 Tested

AID:: 1956153

Summary Compounds, Active PubMed Citation

Select item 195615020.

Antibacterial activity against methicillin resistant Staphylococcus aureus assessed as reduction in bacterial growth at 1 times MIC by time kill assay

Source:: ChEMBL

Assay data:3 Active, 3 Tested

AID:: 1956150

Summary Compounds, Active PubMed Citation

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Target

Proteins (2)
BioAssays with protein sequences specified as targets

BioActivity

Active Compounds (1,000)
BioAssays with compounds reported as biologically active
Activity (IC50, etc) ≤ 1 nM (13)
BioAssays with the active concentration of tested reagents less than 1 nanomolar
Activity (IC50, etc) ≤ 1 µM (457)
BioAssays with the active concentration of tested reagents less than 1 micromolar

Experiment Type

Summary (1)
BioAssays summarizing information from multiple assays for validated chemical probes or small molecule leads
Confirmatory (641)
Low-throughput BioAssays where the activity outcome is based on a dose-response relationship with multiple tested concentrations

Assay Project (3)
BioAssays organized into assay projects based on linkage to Summary assays. Click an project below to retrieve the bioassay list for the project. Click 'All Assay Projects' to retrieve all assay projects represented by Summary assays.

Depositor Category

Literature Extraction (993)
BioAssays extracted from the literature
NIH MLP (2)
BioAssays deposited by the NIH Molecular Libraries Program
Other (5)
BioAssays deposited by other experimentalists

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