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Cytotoxicity against HEK293 cells assessed as reduction in cell viability after 48 hrs by MTT assay
Assay data:16 Active, 25 Tested
SummaryCompounds, ActivePubMed Citation
Inhibition of human DNA topoisomerase 2alpha-mediated decatenation of kinetoplast DNA at 100 uM after 30 mins by agarose gel electrophoresis
Assay data:24 Active, 24 Tested
SummaryCompounds, ActivePubMed CitationRelated BioAssays by Target
Experimentally measured binding affinity data (IC50) for protein-ligand complexes derived from PDB
Assay data:4302 Active, 250 Activity ≤ 1 nM, 2931 Activity ≤ 1 µM, 4302 Tested
SummaryCompounds, ActiveCompounds, activity ≤ 1 µMPubMed CitationRelated BioAssays by DepositorRelated BioAssays by Target
Inhibition of human TNKS1 (1030 to 1317) using NAD+ as substrate by fluorescence assay
Assay data:22 Active, 21 Activity ≤ 1 µM, 32 Tested
SummaryCompounds, ActiveCompounds, activity ≤ 1 µMPubMed CitationRelated BioAssays by Target
Counterscreen for activators of the function of SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 2 (SMARCA2, BRM): Luminescence-based cell-based high throughput screening assay to identify non-selective compounds using the VP16 reporter assay
Assay data:1427 Active, 3499 Tested
SummaryCompounds, ActivePubMed CitationRelated BioAssays by DepositorRelated BioAssays by Same Project
Luminescence-based cell-based primary high throughput screening assay to identify activators of the function of SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 2 (SMARCA2, BRM)
Assay data:3838 Active, 369245 Tested
SummaryCompounds, ActivePubMed CitationRelated BioAssays by DepositorRelated BioAssays by Same ProjectRelated BioAssays by Target
Counterscreen for inhibitors of the fructose-bisphosphate aldolase (FBA) of M. tuberculosis: Absorbance-based biochemical high throughput Glycerophosphate Dehydrogenase-Triosephosphate Isomerase (GDH-TPI) full deck assay to identify assay artifacts
Assay data:4455 Active, 356407 Tested
qHTS screen for small molecules that induce genotoxicity in human embryonic kidney (HEK293T) cells expressing luciferase-tagged ELG1
Assay data:4174 Active, 2 Activity ≤ 1 nM, 1213 Activity ≤ 1 µM, 330308 Tested
SummaryCompounds, ActiveCompounds, activity ≤ 1 µMRelated BioAssays by DepositorRelated BioAssays by Same ProjectRelated BioAssays by Target
qHTS Assay for NPC1 Promoter Activators
Assay data:7586 Active, 12 Activity ≤ 1 nM, 2657 Activity ≤ 1 µM, 321376 Tested
SummaryCompounds, ActiveCompounds, activity ≤ 1 µMPubMed CitationRelated BioAssays by DepositorRelated BioAssays by Same ProjectRelated BioAssays by Target
qHTS Assay for Rab9 Promoter Activators
Assay data:9143 Active, 10 Activity ≤ 1 nM, 3391 Activity ≤ 1 µM, 321297 Tested
uHTS Luminescent assay for identification of inhibitors of Sentrin-specific protease 7 (SENP7)
Assay data:4906 Active, 331759 Tested
Counterscreen for activators of the Aryl Hydrocarbon Receptor (AHR): luminescence-based cell-based high throughput screening assay to identify activators of the Pregnane X Receptor (PXR)
Assay data:2017 Active, 2281 Tested
qHTS Assay for Enhancers of SMN2 Splice Variant Expression
Assay data:5854 Active, 11 Activity ≤ 1 nM, 5217 Activity ≤ 1 µM, 211511 Tested
Luminescence-based cell-based high throughput confirmation assay for activators of the Aryl Hydrocarbon Receptor (AHR)
Assay data:1982 Active, 2281 Tested
Luminescence-based primary cell-based high throughput screening assay to identify activators of the Aryl Hydrocarbon Receptor (AHR)
Assay data:7990 Active, 324858 Tested
Cycloheximide Counterscreen for Small Molecule Inhibitors of Shiga Toxin
Assay data:37055 Active, 296456 Tested
MLPCN Alpha-Synuclein 5'UTR - 5'-UTR binding - activators
Assay data:21692 Active, 303857 Tested
Primary biochemical High Throughput Screening assay for agonists of the steroid receptor coactivator 2 (SRC-2) recruitment by the peroxisome proliferator-activated receptor gamma (PPARgamma)
Assay data:670 Active, 196255 Tested
Profiling the NIH Molecular Libraries Small Molecule Repository: Autofluorescence at 339/460 nm
Assay data:3590 Active, 65445 Tested
SummaryCompounds, ActiveRelated BioAssays by Depositor
Primary biochemical High Throughput Screening assay for agonists of the steroid receptor coactivator 1 (SRC-1) recruitment by the peroxisome proliferator-activated receptor gamma (PPARgamma)
Assay data:811 Active, 196256 Tested
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