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Antiviral activity against Dengue virus serotype 2 New Guinea C infected at 100 TCID50 in human HuH7 cells assessed as reduction of NS5 positive cells at 20 uM measured at 48 to 72 hrs post-infection by Alexa fluor 488 dye based confocal microscopy
Assay data:1 Active, 1 Tested
SummaryCompounds, ActivePubMed Citation
Antiviral activity against Dengue virus serotype 2 New Guinea C infected at 100 TCID50 in human HuH7 cells assessed as increase in viable cells at 20 uM measured at 48 to 72 hrs post-infection by Alexa fluor 488 dye based confocal microscopy
Induction of DDX3X recruitment in human HuH7 cells infected with 100 TCID50 of Dengue virus serotype 2 New Guinea C assessed as increase in DDX3X expression in perinuclear region at 20 uM measured at 48 to 72 hrs post-infection by Alexa fluor 488 dye based confocal microscopy
SummaryCompounds, ActivePubMed CitationRelated BioAssays by Target
Antiviral activity against Dengue virus serotype 2 New Guinea C infected at 100 TCID50 in human HuH7 cells assessed as cytoplasmic localization of NS5 followed by movement to nucleus at 20 uM measured at 6 hrs post-infection by Alexa fluor 488 dye based confocal microscopy
Induction of DDX3X recruitment in human HuH7 cells infected with 100 TCID50 of Dengue virus serotype 2 New Guinea C assessed as colocalization of DDX3X in perinuclear region at 20 uM measured at 6 to 24 hrs post-infection by Alexa fluor 488 dye based confocal microscopy
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