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Inhibition of Shigella dysenteriae Alexa-488 labelled STXB retrograde transport from endosome to trans golgi network in human HeLa cells at 1 uM incubated with cells for 1 hr prior to STXB challenge incubated for 30 mins in ice followed by 45 mins incubation at 37 degC by phalloidin-Atto-550/DAPI staining based confocal microscopic analysis
Assay data:1 Active, 2 Tested
SummaryCompounds, ActivePubMed CitationRelated BioAssays by Target
Inhibition of Escherichia coli Stx2 in human HeLa cells assessed as stimulation of protein synthesis by measuring increase in [14C]-leucine incorporation incubated with cells for 4 hrs prior to Stx2 addition and further incubated for 20 hrs and subsequent [14C]-leucine addition measured after 6 hrs by microbeta liquid scintillation counting analysis
Assay data:15 Active, 4 Activity ≤ 1 µM, 59 Tested
SummaryCompounds, ActiveCompounds, activity ≤ 1 µMPubMed Citation
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