BioAssays, Active for PubChem Compound (Select 134157838) - PubChem BioAssay - NCBI

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Items: 11

Select item 18533001.

Cytotoxicity against human HL-60 cells assessed as cell growth inhibition incubated for 72 hrs by MTT assay

Source:: ChEMBL

Assay data:49 Active, 38 Activity ≤ 1 µM, 50 Tested

AID:: 1853300

Summary Compounds, Active Compounds, activity ≤ 1 µM PubMed Citation

Select item 18532982.

Cytotoxicity against human HCT-116 cells assessed as cell growth inhibition incubated for 72 hrs by MTT assay

Source:: ChEMBL

Assay data:49 Active, 15 Activity ≤ 1 µM, 50 Tested

AID:: 1853298

Summary Compounds, Active Compounds, activity ≤ 1 µM PubMed Citation

Select item 13264013.

Cytotoxicity against NQO1-deficient mouse L929 cells assessed as reduction in cell viability after 72 hrs by MTT assay

Source:: ChEMBL

Assay data:23 Active, 3 Activity ≤ 1 µM, 26 Tested

AID:: 1326401

Summary Compounds, Active Compounds, activity ≤ 1 µM PubMed Citation

Select item 13264004.

Cytotoxicity against NQO1-deficient chinese hamster V79 cells assessed as reduction in cell viability after 72 hrs by MTT assay

Source:: ChEMBL

Assay data:23 Active, 3 Activity ≤ 1 µM, 26 Tested

AID:: 1326400

Summary Compounds, Active Compounds, activity ≤ 1 µM PubMed Citation

Select item 13263995.

Cytotoxicity against NQO1-deficient human PBMC assessed as reduction in cell viability after 72 hrs by MTT assay

Source:: ChEMBL

Assay data:22 Active, 1 Activity ≤ 1 µM, 27 Tested

AID:: 1326399

Summary Compounds, Active Compounds, activity ≤ 1 µM PubMed Citation

Select item 13263986.

Cytotoxicity against human OVCAR8 cells overexpressing NQO1 assessed as reduction in cell viability after 72 hrs by MTT assay

Source:: ChEMBL

Assay data:24 Active, 8 Activity ≤ 1 µM, 27 Tested

AID:: 1326398

Summary Compounds, Active Compounds, activity ≤ 1 µM PubMed Citation

Select item 13263977.

Cytotoxicity against human MDA-MB-435 cells overexpressing NQO1 assessed as reduction in cell viability after 72 hrs by MTT assay

Source:: ChEMBL

Assay data:23 Active, 8 Activity ≤ 1 µM, 26 Tested

AID:: 1326397

Summary Compounds, Active Compounds, activity ≤ 1 µM PubMed Citation

Select item 13263968.

Cytotoxicity against human SF295 cells overexpressing NQO1 assessed as reduction in cell viability after 72 hrs by MTT assay

Source:: ChEMBL

Assay data:21 Active, 8 Activity ≤ 1 µM, 25 Tested

AID:: 1326396

Summary Compounds, Active Compounds, activity ≤ 1 µM PubMed Citation

Select item 13263959.

Cytotoxicity against human PC3 cells overexpressing NQO1 assessed as reduction in cell viability after 72 hrs by MTT assay

Source:: ChEMBL

Assay data:24 Active, 5 Activity ≤ 1 µM, 27 Tested

AID:: 1326395

Summary Compounds, Active Compounds, activity ≤ 1 µM PubMed Citation

Select item 132639410.

Cytotoxicity against human HCT116 cells expressing NQO1 assessed as reduction in cell viability after 72 hrs by MTT assay

Source:: ChEMBL

Assay data:24 Active, 7 Activity ≤ 1 µM, 27 Tested

AID:: 1326394

Summary Compounds, Active Compounds, activity ≤ 1 µM PubMed Citation

Select item 132639311.

Cytotoxicity against NQO1-deficient human HL60 cells assessed as reduction in cell viability after 72 hrs by MTT assay

Source:: ChEMBL

Assay data:22 Active, 7 Activity ≤ 1 µM, 25 Tested

AID:: 1326393

Summary Compounds, Active Compounds, activity ≤ 1 µM PubMed Citation

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BioActivity

Active Compounds (11)
BioAssays with compounds reported as biologically active
Activity (IC50, etc) ≤ 1 µM (11)
BioAssays with the active concentration of tested reagents less than 1 micromolar

Experiment Type

Confirmatory (11)
Low-throughput BioAssays where the activity outcome is based on a dose-response relationship with multiple tested concentrations

Depositor Category

Literature Extraction (11)
BioAssays extracted from the literature

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