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Human pregnane X receptor (PXR) small molecule agonists, qHTS assay
Assay data:2218 Active, 1 Activity ≤ 1 nM, 106 Activity ≤ 1 µM, 9667 Tested
SummaryCompounds, ActiveCompounds, activity ≤ 1 µMRelated BioAssays by DepositorRelated BioAssays by Same ProjectRelated BioAssays by Target
Human bromodomain containing 4 (Bromodomain kinase (BRDK) family)
Assay data:29 Active, 29 Tested
SummaryCompounds, ActivePubMed CitationRelated BioAssays by Target
CCRIS carcinogenicity studies
Assay data:1139 Active, 1767 Tested
SummaryCompounds, Active
qHTS assay to identify small molecule agonists of the retinoic acid receptor (RAR) signaling pathway
Assay data:429 Active, 2 Activity ≤ 1 nM, 171 Activity ≤ 1 µM, 9315 Tested
SummaryCompounds, ActiveCompounds, activity ≤ 1 µMRelated BioAssays by Target
Experimentally measured binding affinity data (IC50) for protein-ligand complexes derived from PDB
Assay data:4302 Active, 250 Activity ≤ 1 nM, 2931 Activity ≤ 1 µM, 4302 Tested
SummaryCompounds, ActiveCompounds, activity ≤ 1 µMPubMed CitationRelated BioAssays by DepositorRelated BioAssays by Target
DSSTox (CPDBAS) Carcinogenic Potency Database Summary MultiCellCall Results
Assay data:582 Active, 1152 Tested
SummaryCompounds, ActivePubMed Citation
DSSTox (CPDBAS) Carcinogenic Potency Database Summary Mouse Bioassay Results
Assay data:445 Active, 1007 Tested
DSSTox (CPDBAS) Carcinogenic Potency Database Summary SingleCellCall Results
Assay data:806 Active, 1547 Tested
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