BioAssays for PubChem Compound (Select 91826679) - PubChem BioAssay - NCBI

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Select item 16781321.

Binding affinity to N-terminal GST tagged human ATAD2B short form expressed in Escherichia coli by ITC analysis

Source:: ChEMBL

Protein Target:: ATPase family AAA domain-containing protein 2B

Assay data:7 Tested

AID:: 1678132

Summary PubMed Citation Related BioAssays by Target

Select item 16781282.

Binding affinity to N-terminal GST tagged human ATAD2 expressed in Escherichia coli by ITC analysis

Source:: ChEMBL

Protein Target:: ATPase family AAA domain-containing protein 2

Assay data:1 Active, 1 Activity ≤ 1 µM, 1 Tested

AID:: 1678128

Summary Compounds, Active Compounds, activity ≤ 1 µM PubMed Citation Related BioAssays by Target

Select item 16781253.

Binding affinity to N-terminal GST tagged human ATAD2B (953-1085 residues) expressed in Escherichia coli by ITC analysis

Source:: ChEMBL

Protein Target:: ATPase family AAA domain-containing protein 2B

Assay data:2 Active, 1 Activity ≤ 1 µM, 20 Tested

AID:: 1678125

Summary Compounds, Active Compounds, activity ≤ 1 µM PubMed Citation Related BioAssays by Target

Select item 14005314.

Selectivity for N-terminal FLAG-6His-tagged TEV-fused ATAD2 (981 to 1121 residues) (unknown origin) over 6His-tagged Thr-BRD4(BD1) (1 to 477 residues) (unknown origin) by TR-FRET assay

Source:: ChEMBL

Assay data:14 Tested

AID:: 1400531

Summary PubMed Citation

Select item 14005305.

Inhibition of 6His-tagged Thr-BRD4 (BD1) (1 to 477 residues) (unknown origin) expressed in Escherichia coli BL21(DE3) after 30 mins in presence of biotinylated triacetylated histone H4 peptide by alexa fluor 647 dyse based TR-FRET assay

Source:: ChEMBL

Protein Target:: Bromodomain-containing protein 4

Assay data:14 Active, 1 Activity ≤ 1 µM, 20 Tested

AID:: 1400530

Summary Compounds, Active Compounds, activity ≤ 1 µM PubMed Citation Related BioAssays by Target

Select item 14005296.

Inhibition of N-terminal FLAG-6His-tagged TEV-fused ATAD2 (981 to 1121 residues) (unknown origin) expressed in Escherichia coli BL21(DE3) after 30 mins in presence of biotinylated triacetylated histone H4 peptide by alexa fluor 488-dye based TR-FRET assay

Source:: ChEMBL

Protein Target:: ATPase family AAA domain-containing protein 2

Assay data:15 Active, 13 Activity ≤ 1 µM, 20 Tested

AID:: 1400529

Summary Compounds, Active Compounds, activity ≤ 1 µM PubMed Citation Related BioAssays by Target

Select item 12344077.

Binding affinity to TAF1 in human HUT78 cells incubated for 45 mins by mass spectrometry based bromosphere chemoproteomic assay

Source:: ChEMBL

Protein Target:: Transcription initiation factor TFIID subunit 1

Assay data:2 Active, 3 Tested

AID:: 1234407

Summary Compounds, Active PubMed Citation Related BioAssays by Target

Select item 12344058.

Binding affinity to PBRM1 in human HUT78 cells incubated for 45 mins by mass spectrometry based bromosphere chemoproteomic assay

Source:: ChEMBL

Protein Target:: Protein polybromo-1

Assay data:1 Active, 3 Tested

AID:: 1234405

Summary Compounds, Active PubMed Citation Related BioAssays by Target

Select item 12344049.

Binding affinity to KAT2B in human HUT78 cells incubated for 45 mins by mass spectrometry based bromosphere chemoproteomic assay

Source:: ChEMBL

Protein Target:: Histone acetyltransferase KAT2B

Assay data:2 Tested

AID:: 1234404

Summary PubMed Citation Related BioAssays by Target

Select item 123440310.

Binding affinity to KAT2A in human HUT78 cells incubated for 45 mins by mass spectrometry based bromosphere chemoproteomic assay

Source:: ChEMBL

Protein Target:: Histone acetyltransferase KAT2A

Assay data:3 Tested

AID:: 1234403

Summary PubMed Citation Related BioAssays by Target

Select item 123440211.

Binding affinity to BRPF1 in human HUT78 cells incubated for 45 mins by mass spectrometry based bromosphere chemoproteomic assay

Source:: ChEMBL

Protein Target:: Peregrin

Assay data:3 Tested

AID:: 1234402

Summary PubMed Citation Related BioAssays by Target

Select item 123440112.

Binding affinity to BRDT in human HUT78 cells incubated for 45 mins by mass spectrometry based bromosphere chemoproteomic assay

Source:: ChEMBL

Protein Target:: Bromodomain testis-specific protein

Assay data:1 Active, 1 Tested

AID:: 1234401

Summary Compounds, Active PubMed Citation Related BioAssays by Target

Select item 123440013.

Binding affinity to BRD9 in human HUT78 cells incubated for 45 mins by mass spectrometry based bromosphere chemoproteomic assay

Source:: ChEMBL

Protein Target:: Bromodomain-containing protein 9

Assay data:1 Active, 3 Tested

AID:: 1234400

Summary Compounds, Active PubMed Citation Related BioAssays by Target

Select item 123439914.

Binding affinity to BRD8 in human HUT78 cells incubated for 45 mins by mass spectrometry based bromosphere chemoproteomic assay

Source:: ChEMBL

Protein Target:: Bromodomain-containing protein 8

Assay data:1 Active, 1 Tested

AID:: 1234399

Summary Compounds, Active PubMed Citation Related BioAssays by Target

Select item 123439815.

Binding affinity to BRD7 in human HUT78 cells incubated for 45 mins by mass spectrometry based bromosphere chemoproteomic assay

Source:: ChEMBL

Protein Target:: Bromodomain-containing protein 7

Assay data:1 Active, 2 Tested

AID:: 1234398

Summary Compounds, Active PubMed Citation Related BioAssays by Target

Select item 123439716.

Binding affinity to BRD4 in human HUT78 cells incubated for 45 mins by mass spectrometry based bromosphere chemoproteomic assay

Source:: ChEMBL

Protein Target:: Bromodomain-containing protein 4

Assay data:2 Active, 3 Tested

AID:: 1234397

Summary Compounds, Active PubMed Citation Related BioAssays by Target

Select item 123439617.

Binding affinity to BRD3 in human HUT78 cells incubated for 45 mins by mass spectrometry based bromosphere chemoproteomic assay

Source:: ChEMBL

Protein Target:: Bromodomain-containing protein 3

Assay data:2 Active, 1 Activity ≤ 1 µM, 3 Tested

AID:: 1234396

Summary Compounds, Active Compounds, activity ≤ 1 µM PubMed Citation Related BioAssays by Target

Select item 123439518.

Binding affinity to BRD2 in human HUT78 cells incubated for 45 mins by mass spectrometry based bromosphere chemoproteomic assay

Source:: ChEMBL

Protein Target:: Bromodomain-containing protein 2

Assay data:2 Active, 1 Activity ≤ 1 µM, 3 Tested

AID:: 1234395

Summary Compounds, Active Compounds, activity ≤ 1 µM PubMed Citation Related BioAssays by Target

Select item 123439419.

Binding affinity to BPTF in human HUT78 cells incubated for 45 mins by mass spectrometry based bromosphere chemoproteomic assay

Source:: ChEMBL

Protein Target:: Nucleosome-remodeling factor subunit BPTF

Assay data:3 Tested

AID:: 1234394

Summary PubMed Citation Related BioAssays by Target

Select item 123439320.

Binding affinity to BAZ2B in human HUT78 cells incubated for 45 mins by mass spectrometry based bromosphere chemoproteomic assay

Source:: ChEMBL

Protein Target:: Bromodomain adjacent to zinc finger domain protein 2B

Assay data:1 Active, 3 Tested

AID:: 1234393

Summary Compounds, Active PubMed Citation Related BioAssays by Target

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BioActivity

Active Compounds (20)
BioAssays with compounds reported as biologically active
Activity (IC50, etc) ≤ 1 µM (11)
BioAssays with the active concentration of tested reagents less than 1 micromolar

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Confirmatory (26)
Low-throughput BioAssays where the activity outcome is based on a dose-response relationship with multiple tested concentrations

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Literature Extraction (30)
BioAssays extracted from the literature

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