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Inhibition of human amyloid beta (1 to 40) assessed as reduction in aggregation measured after 24 hrs by ThT fluorescence assay
Assay data:6 Active, 29 Tested
SummaryCompounds, ActivePubMed CitationRelated BioAssays by Target
Inhibition of Dengue virus 2 RdRp using homopolymeric uridine RNA as template assessed as reduction in RNA synthesis incubated for 10 mins by picogreen fluorescent assay
Assay data:8 Active, 1 Activity ≤ 1 µM, 27 Tested
SummaryCompounds, ActiveCompounds, activity ≤ 1 µMPubMed Citation
Neuroprotective activity against 0.1 uM amyloid beta 42-induced toxicity in rat PC12 cells assessed as cell viability at 10 uM after 24 hrs by MTT assay
Assay data:24 Tested
SummaryPubMed Citation
Inhibition of BACE1 after 60 mins by FRET assay
Assay data:11 Active, 3 Activity ≤ 1 µM, 21 Tested
SummaryCompounds, ActiveCompounds, activity ≤ 1 µMPubMed CitationRelated BioAssays by Target
Inhibition of Influenza A PR/8/34 H1N1 virus neuraminidase activity by MUN-ANA substrate based fluorimetric assay
Assay data:27 Tested
SummaryPubMed CitationRelated BioAssays by Target
Inhibition of procoagulant activity in monocyte from human blood assessed as counteraction of endotoxin-induced tissue factor expression after 18 hrs
Assay data:1 Active, 1 Activity ≤ 1 µM, 1 Tested
Inhibition of procoagulant activity in monocyte from human blood assessed as counteraction of IL1-induced tissue factor expression after 18 hrs
Assay data:21 Active, 1 Activity ≤ 1 µM, 21 Tested
Inhibition of procoagulant activity in monocyte from human blood assessed as counteraction of IL1-induced tissue factor expression at 10 uM after 18 hrs measured as microunits of tissue factor/10'5 cells
Assay data:42 Tested
Selectivity index, ratio of IC50 for human PBMC to EC50 for HIV1 LAV-1
Assay data:7 Tested
Cytotoxicity against uninfected PHA-stimulated human PBMC assessed as thymidine incorporation after 24 hrs by trypan blue exclusion method
Assay data:1 Active, 7 Tested
SummaryCompounds, ActivePubMed Citation
Antiviral activity against HIV1 LAV-1 in PHA-stimulated human PBMC after 6 days
Assay data:3 Active, 1 Activity ≤ 1 µM, 7 Tested
Inhibition of HIV1 recombinant reverse transcriptase p66/p51 expressed in Escherichia coli at 200 ug/mL
Assay data:16 Tested
Inhibition of HIV1 recombinant reverse transcriptase p66/p51 expressed in Escherichia coli
Assay data:18 Tested
Inhibition of human Cathepsin K
Assay data:8 Tested
Antituberculosis activity against Mycobacterium tuberculosis at a concentration of 12.5 ug/mL
Assay data:28 Tested
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