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Selectivity ratio of Ki for PTP1B (unknown origin) to Ki for TCPTP (unknown origin)
Assay data:5 Tested
SummaryPubMed Citation
Inhibition of PTP1B (unknown origin) assessed as inhibition constant
Assay data:7 Active, 1 Activity ≤ 1 nM, 5 Activity ≤ 1 µM, 8 Tested
SummaryCompounds, ActiveCompounds, activity ≤ 1 µMPubMed CitationRelated BioAssays by Target
PTP1B and TCPTP Inhibition Assay from Article 10.1016/j.bmcl.2004.08.063: "Isoxazole carboxylic acids as protein tyrosine phosphatase 1B (PTP1B) inhibitors."
Assay data:3 Active, 1 Activity ≤ 1 µM, 8 Tested
Selectivity ratio of IC50 for TCPTP (unknown origin) to IC50 for PTP1B (unknown origin)
Assay data:1 Tested
Inhibition of PTP1B (unknown origin)
Assay data:1 Active, 1 Activity ≤ 1 µM, 1 Tested
Inhibition of TCPTP (unknown origin)
Assay data:3 Active, 3 Activity ≤ 1 µM, 5 Tested
Experimentally measured binding affinity data (Ki) for protein-ligand complexes derived from PDB
Assay data:3598 Active, 421 Activity ≤ 1 nM, 2233 Activity ≤ 1 µM, 3598 Tested
SummaryCompounds, ActiveCompounds, activity ≤ 1 µMPubMed CitationRelated BioAssays by DepositorRelated BioAssays by Target
Binding affinity for mouse protein-tyrosine phosphatase 1B (PTP1B) expressed in COS 7 cells
Binding affinity for T-cell Protein tyrosine phosphatase (TCPTP)
Assay data:3 Tested
SummaryPubMed CitationRelated BioAssays by Target
Experimentally measured binding affinity data derived from PDB
Assay data:3073 Active, 3073 Tested
SummaryCompounds, ActivePubMed CitationRelated BioAssays by Target
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