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Enzymatic assay of human HDAC6 with custom peptide substrate
Assay data:5603 Tested
SummaryRelated BioAssays by Target
Enzymatic assay of human HDAC6 with commercial peptide substrate
Antiviral activity determined as inhibition of SARS-CoV-2 induced cytotoxicity of VERO-6 cells at 10 uM after 48 hours exposure to 0.01 MOI SARS CoV-2 virus by high content imaging
Assay data:2 Activity ≤ 1 µM, 4309 Tested
SummaryCompounds, activity ≤ 1 µM
Assay data:7212 Tested
Summary
SARS-CoV-2 3CL-Pro protease inhibition percentage at 20 M by FRET kind of response from peptide substrate
Liver toxicity in human assessed as induction of drug-induced liver injury by measuring verified drug-induced liver injury concern status
Assay data:929 Tested
SummaryPubMed Citation
Liver toxicity in human assessed as induction of drug-induced liver injury by measuring severity class index
Antiviral activity determined as inhibition of SARS-CoV-2 induced cytotoxicity of Caco-2 cells at 10 uM after 48 hours by high content imaging
Assay data:5612 Tested
Human M5 receptor (Acetylcholine receptors (muscarinic))
Assay data:54 Active, 54 Tested
SummaryCompounds, ActivePubMed CitationRelated BioAssays by Target
Human M4 receptor (Acetylcholine receptors (muscarinic))
Assay data:77 Active, 77 Tested
Human M3 receptor (Acetylcholine receptors (muscarinic))
Human M2 receptor (Acetylcholine receptors (muscarinic))
Assay data:92 Active, 92 Tested
Human M1 receptor (Acetylcholine receptors (muscarinic))
Assay data:96 Active, 96 Tested
SSB-PriA antibiotic resistant target AlphaScreen
Assay data:2577 Active, 432182 Tested
SummaryCompounds, ActivePubMed CitationRelated BioAssays by DepositorRelated BioAssays by Target
Primary cell-based high-throughput screening assay for identification of small molecule agonists of Aedes aegypti NPYLR7 [Small Molecule Inhibitors of Mosquito Biting Behavior]
Assay data:412 Active, 270665 Tested
SummaryCompounds, ActivePubMed CitationRelated BioAssays by Depositor
Toxoplasma gondii HTS in the absence of IFN-y
Assay data:614 Active, 6425 Tested
SummaryCompounds, ActiveRelated BioAssays by DepositorRelated BioAssays by Target
Toxoplasma gondii inhibition HTS in the presence of IFN-y
Assay data:2597 Active, 69085 Tested
mouse cGAS chemiluminescence screen
Assay data:241 Active, 161421 Tested
human cGAS chemiluminescence screen
Assay data:234 Active, 287414 Tested
mouse cGAS RapidFire screen
Assay data:231 Active, 125931 Tested
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