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Carcinogenesis bioassays from the Carcinogenic Potency Database (CPDB)
Assay data:1547 Tested
Summary
CCRIS carcinogenicity studies
Assay data:1139 Active, 1767 Tested
SummaryCompounds, Active
CCRIS mutagenicity studies
Assay data:4929 Active, 8266 Tested
Potency index, ratio of LD50 for fenvalerate-resistant Helicoverpa armigera HDFR third-instar larvae injected with TE buffer to LD50 for fenvalerate-resistant Helicoverpa armigera HDFR third-instar larvae injected with dsCYP6B7-313-1 dsRNA after 24 hr
Assay data:1 Tested
SummaryPubMed Citation
Insecticidal activity against fenvalerate-resistant Helicoverpa armigera HDFR third-instar larvae injected with dsCYP6B7-313-1 dsRNA plus dsCyt-b5-4 dsRNA assessed as insect mortality at 4 to 16 ug/larva after 48 hr (fenvalerate alone control = 29.1 to 50.0%)
Insecticidal activity against fenvalerate-resistant Helicoverpa armigera HDFR third-instar larvae injected with dsCYP6B7-313-1 dsRNA plus dsCPR-403-1 dsRNA and dsCyt-b5-4 dsRNA assessed as insect mortality at 4 to 16 ug/larva after 48 hr (fenvalerate alone control = 29.1 to 50.0%)
Insecticidal activity against fenvalerate-susceptible Helicoverpa armigera third-instar larvae assessed as compound level per larva causing mortality after 48 hr
Insecticidal activity against fenvalerate-resistant Helicoverpa armigera HDFR third-instar larvae assessed as compound level per larva causing mortality after 48 hr
Resistance index, ratio of LD50 for fenvalerate-resistant Helicoverpa armigera HDFR third-instar larvae to LD50 for fenvalerate-susceptible Helicoverpa armigera third-instar larvae
Insecticidal activity against fenvalerate-resistant Helicoverpa armigera HDFR third-instar larvae without dsRNA injection assessed as compound level per larva causing mortality after 12 hr
Insecticidal activity against fenvalerate-resistant Helicoverpa armigera HDFR third-instar larvae injected with TE buffer assessed as compound level per larva causing mortality after 12 hr
Insecticidal activity against fenvalerate-resistant Helicoverpa armigera HDFR third-instar larvae injected with dsCYP6B7-313-1 dsRNA assessed as compound level per larva causing mortality after 12 hr
Insecticidal activity against fenvalerate-resistant Helicoverpa armigera HDFR third-instar larvae injected with dsCYP6B7-313-1 dsRNA plus dsCPR-403-1 dsRNA assessed as compound level per larva causing mortality after 12 hr
Insecticidal activity against fenvalerate-resistant Helicoverpa armigera HDFR third-instar larvae injected with dsCYP6B7-313-1 dsRNA plus dsCyt-b5-4 dsRNA assessed as compound level per larva causing mortality after 12 hr
Insecticidal activity against fenvalerate-resistant Helicoverpa armigera HDFR third-instar larvae injected with dsCYP6B7-313-1 dsRNA plus dsCPR-403-1 dsRNA and dsCyt-b5-4 dsRNA assessed as compound level per larva causing mortality after 12 hr
Insecticidal activity against fenvalerate-resistant Helicoverpa armigera HDFR third-instar larvae without dsRNA injection assessed as compound level per larva causing mortality after 24 hr
Insecticidal activity against fenvalerate-resistant Helicoverpa armigera HDFR third-instar larvae injected with TE buffer assessed as compound level per larva causing mortality after 24 hr
Insecticidal activity against fenvalerate-resistant Helicoverpa armigera HDFR third-instar larvae injected with dsCYP6B7-313-1 dsRNA assessed as compound level per larva causing mortality after 24 hr
Insecticidal activity against fenvalerate-resistant Helicoverpa armigera HDFR third-instar larvae injected with dsCYP6B7-313-1 dsRNA plus dsCPR-403-1 dsRNA assessed as compound level per larva causing mortality after 24 hr
Insecticidal activity against fenvalerate-resistant Helicoverpa armigera HDFR third-instar larvae injected with dsCYP6B7-313-1 dsRNA plus dsCyt-b5-4 dsRNA assessed as compound level per larva causing mortality after 24 hr
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