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High-throughput screening primary assay to identify small molecule activators of human guanylyl cyclase B (GC-B) receptor activity
Assay data:399 Active, 370620 Tested
SummaryCompounds, Active
Discovery of Small Molecules to Inhibit Human Cytomegalovirus Nuclear Egress
Assay data:281 Active, 189401 Tested
Primary qHTS for Inhibitors of ATXN expression
Assay data:2593 Active, 3 Activity ≤ 1 nM, 2671 Activity ≤ 1 µM, 361713 Tested
SummaryCompounds, ActiveCompounds, activity ≤ 1 µMPubMed CitationRelated BioAssays by DepositorRelated BioAssays by Target
High-throughput screening primary assay to identify small molecule activators of human GC-A enzyme activity
Assay data:519 Active, 370620 Tested
Primary qHTS assay for inhibitors of human arachidonate 12S-lipoxygenase (ALOX12): Round 2
Assay data:6069 Active, 5332 Activity ≤ 1 µM, 575118 Tested
SummaryCompounds, ActiveCompounds, activity ≤ 1 µMRelated BioAssays by DepositorRelated BioAssays by Target
Non-competitive inhibition of Saccharomyces cerevisiae alpha-glucosidase assessed as substrate Vmax incubated for 30 mins before pNPG substrate addition and measured after 10 mins by spectrophotometry based Michaelis-Menten equation and Lineweaver-Burk plot analysis
Assay data:1 Tested
SummaryPubMed Citation
Non-competitive inhibition of Saccharomyces cerevisiae alpha-glucosidase assessed as substrate Km incubated for 30 mins before pNPG substrate addition and measured after 10 mins by spectrophotometry based Michaelis-Menten equation and Lineweaver-Burk plot analysis
Inhibition of Saccharomyces cerevisiae alpha-glucosidase incubated for 30 mins before pNPG substrate addition and measured after 10 mins by spectrophotometry
Inhibition of Saccharomyces cerevisiae alpha-glucosidase at 27.62 uM incubated for 30 mins before pNPG substrate addition and measured after 10 mins by spectrophotometry relative to untreated control
Inhibition of Saccharomyces cerevisiae alpha-glucosidase at 3.54 uM incubated for 30 mins before pNPG substrate addition and measured after 10 mins by spectrophotometry relative to untreated control
Cell-based high throughput primary assay to identify activators of GPR151
Assay data:6756 Active, 646675 Tested
SummaryCompounds, ActiveRelated BioAssays by DepositorRelated BioAssays by Target
Antagonist identification of Pyk2 oligomerization: high-throughput screening cellular assay
Assay data:818 Active, 98760 Tested
qHTS for Suppressors of FUS Proteinopathy: Primary screen using FUS-linked yeast assay
Assay data:932 Active, 388864 Tested
SummaryCompounds, ActiveRelated BioAssays by Target
qHTS assay for MDR1-selective chemotherapeutics: Primary screen using the drug-selected MDR subline cells KB-V1
Assay data:13449 Active, 399619 Tested
SummaryCompounds, ActiveRelated BioAssays by Depositor
qHTS assay for MDR1-selective chemotherapeutics: Primary screen using the parental adenocarcinoma cell KB-3-1
Assay data:5540 Active, 399561 Tested
qHTS for compounds that reverse cellular toxicity of Amyloid beta (A-beta) peptide in yeast: Primary Screen
Assay data:257 Active, 407462 Tested
SummaryCompounds, ActivePubMed CitationRelated BioAssays by DepositorRelated BioAssays by Same ProjectRelated BioAssays by Target
Inhibitor identification of TROY dependent signaling using uHTS single point assay
Assay data:3555 Active, 360980 Tested
qHTS assay for inhibitors of human lactate dehydrogenase
Assay data:736 Active, 484712 Tested
SummaryCompounds, ActivePubMed Citation
qHTS for small molecular inhibitors of PI4K2A
Assay data:535 Active, 419349 Tested
Poison activity at human topoisomerase 2alpha assessed as generation of linear band up to 100 uM using pHOT as substrate incubated for 20 mins by agarose gel electrophoresis
Assay data:9 Tested
SummaryPubMed CitationRelated BioAssays by Target
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