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Cell-based high throughput primary assay to identify activators of GPR151
Assay data:6756 Active, 646675 Tested
SummaryCompounds, ActiveRelated BioAssays by DepositorRelated BioAssays by Target
Luminescence cell-based high throughput primary assay to identify inhibitors of TEAD-YAP interaction.
Assay data:9273 Active, 641570 Tested
SummaryCompounds, ActivePubMed CitationRelated BioAssays by Target
AlphaScreen-based biochemical high throughput primary assay to identify inhibitors of microphthalmia-associated transcription factor (MITF)
Assay data:5861 Active, 646275 Tested
SummaryCompounds, ActivePubMed CitationRelated BioAssays by DepositorRelated BioAssays by Target
AlphaScreen-based biochemical high throughput primary assay to identify activators of the E3 ligase (FBW7).
Assay data:853 Active, 645212 Tested
SummaryCompounds, ActivePubMed Citation
Identification of CBX7 inhibitors - Primary Alpha Screen
Assay data:725 Active, 65740 Tested
SummaryCompounds, Active
Oxadiazole SAR compounds tested via Multiplex dose response to identify specific small molecule inhibitors of Ras and Ras-related GTPases specifically Ras wildtype
Assay data:4 Activity ≤ 1 µM, 51 Tested
SummaryCompounds, activity ≤ 1 µMPubMed CitationRelated BioAssays by DepositorRelated BioAssays by Same ProjectRelated BioAssays by Target
Oxadiazole SAR compounds tested via Multiplex dose response to identify specific small molecule inhibitors of Ras and Ras-related GTPases specifically Rac1 activated mutant
Assay data:30 Active, 2 Activity ≤ 1 µM, 51 Tested
SummaryCompounds, ActiveCompounds, activity ≤ 1 µMPubMed CitationRelated BioAssays by DepositorRelated BioAssays by Same ProjectRelated BioAssays by Target
Oxadiazole SAR compounds tested via Multiplex dose response to identify specific small molecule inhibitors of Ras and Ras-related GTPases specifically Ras activated mutant
Assay data:1 Activity ≤ 1 µM, 51 Tested
Oxadiazole SAR compounds tested via Multiplex dose response to identify specific small molecule inhibitors of Ras and Ras-related GTPases specifically Cdc42 wildtype
Assay data:13 Active, 5 Activity ≤ 1 µM, 51 Tested
Oxadiazole SAR compounds tested via Multiplex dose response to identify specific small molecule inhibitors of Ras and Ras-related GTPases specifically Rab2 wildtype
Assay data:5 Activity ≤ 1 µM, 51 Tested
Oxadiazole SAR compounds tested via Multiplex dose response to identify specific small molecule inhibitors of Ras and Ras-related GTPases specifically Rab7 wildtype
Oxadiazole SAR compounds tested via Multiplex dose response to identify specific small molecule inhibitors of Ras and Ras-related GTPases specifically Rac1 wildtype
Assay data:28 Active, 2 Activity ≤ 1 µM, 51 Tested
Oxadiazole SAR compounds tested by Multiplex dose response to identify specific small molecule inhibitors of Ras and Ras-related GTPases specifically Cdc42 activated mutant
Assay data:37 Active, 7 Activity ≤ 1 µM, 51 Tested
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