BioAssays for PubChem Compound (Select 19649) - PubChem BioAssay - NCBI

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Select item 19639881.

HIV Enzyme Data

Source:: NIAID ChemDB

Assay data:46810 Tested

AID:: 1963988

Select item 19639872.

HIV Cellular Data

Source:: NIAID ChemDB

Assay data:126857 Tested

AID:: 1963987

Select item 19618783.

Binding affinity towards human HRH3 in an in vitro assay with cellular components measured by scintillation counting

Source:: ChEMBL

Protein Target:: Histamine H3 receptor

Assay data:41 Active, 7 Activity ≤ 1 µM, 993 Tested

AID:: 1961878

Summary Compounds, Active Compounds, activity ≤ 1 µM PubMed Citation Related BioAssays by Target

Select item 19618684.

Binding affinity towards human ADRA1A in an in vitro assay with cellular components (NIBR assay) measured by scintillation proximity assay

Source:: ChEMBL

Protein Target:: Alpha-1A adrenergic receptor

Assay data:49 Active, 29 Activity ≤ 1 µM, 231 Tested

AID:: 1961868

Summary Compounds, Active Compounds, activity ≤ 1 µM PubMed Citation Related BioAssays by Target

Select item 19618595.

Binding affinity towards human DRD1 in an in vitro assay with cellular components (NIBR assay) measured by scintillation counting

Source:: ChEMBL

Protein Target:: D(1A) dopamine receptor

Assay data:35 Active, 19 Activity ≤ 1 µM, 305 Tested

AID:: 1961859

Summary Compounds, Active Compounds, activity ≤ 1 µM PubMed Citation Related BioAssays by Target

Select item 19618586.

Antagonist activity at human ADRA1A in an in vitro cell-based assay measured by fluorescence spectroscopy

Source:: ChEMBL

Protein Target:: Alpha-1A adrenergic receptor

Assay data:117 Active, 53 Activity ≤ 1 µM, 881 Tested

AID:: 1961858

Summary Compounds, Active Compounds, activity ≤ 1 µM PubMed Citation Related BioAssays by Target

Select item 19618567.

Binding affinity towards human DRD3 in an in vitro assay with cellular components measured by scintillation counting

Source:: ChEMBL

Protein Target:: D(3) dopamine receptor

Assay data:176 Active, 1 Activity ≤ 1 nM, 87 Activity ≤ 1 µM, 1215 Tested

AID:: 1961856

Summary Compounds, Active Compounds, activity ≤ 1 µM PubMed Citation Related BioAssays by Target

Select item 19618558.

Compound was evaluated for inhibition of human PDE3A in an in vitro cell free assay measured by time-resolved fluorescence resonance energy transfer method

Source:: ChEMBL

Protein Target:: cGMP-inhibited 3',5'-cyclic phosphodiesterase A

Assay data:49 Active, 5 Activity ≤ 1 µM, 1243 Tested

AID:: 1961855

Summary Compounds, Active Compounds, activity ≤ 1 µM PubMed Citation Related BioAssays by Target

Select item 19618539.

Binding affinity towards human HTR1A in an in vitro assay with cellular components measured by scintillation counting

Source:: ChEMBL

Protein Target:: 5-hydroxytryptamine receptor 1A

Assay data:56 Active, 33 Activity ≤ 1 µM, 377 Tested

AID:: 1961853

Summary Compounds, Active Compounds, activity ≤ 1 µM PubMed Citation Related BioAssays by Target

Select item 196185210.

Compound was evaluated for inhibition of human MAOA in an in vitro cell free assay measured by fluorescence spectroscopy

Source:: ChEMBL

Protein Target:: Amine oxidase [flavin-containing] A

Assay data:28 Active, 4 Activity ≤ 1 µM, 1218 Tested

AID:: 1961852

Summary Compounds, Active Compounds, activity ≤ 1 µM PubMed Citation Related BioAssays by Target

Select item 196185111.

Binding affinity towards human OPRM1 in an in vitro assay with cellular components measured by scintillation counting

Source:: ChEMBL

Protein Target:: Mu-type opioid receptor

Assay data:60 Active, 9 Activity ≤ 1 µM, 766 Tested

AID:: 1961851

Summary Compounds, Active Compounds, activity ≤ 1 µM PubMed Citation Related BioAssays by Target

Select item 196185012.

Binding affinity towards human ADRA2A in an in vitro assay with cellular components measured by scintillation counting

Source:: ChEMBL

Protein Target:: Alpha-2A adrenergic receptor

Assay data:63 Active, 20 Activity ≤ 1 µM, 323 Tested

AID:: 1961850

Summary Compounds, Active Compounds, activity ≤ 1 µM PubMed Citation Related BioAssays by Target

Select item 196184913.

Binding affinity towards human SLC6A4 in an in vitro assay with cellular components measured by scintillation counting

Source:: ChEMBL

Protein Target:: Sodium-dependent serotonin transporter

Assay data:148 Active, 75 Activity ≤ 1 µM, 1194 Tested

AID:: 1961849

Summary Compounds, Active Compounds, activity ≤ 1 µM PubMed Citation Related BioAssays by Target

Select item 196184814.

Binding affinity towards human SLC6A2 in an in vitro assay with cellular components measured by scintillation counting

Source:: ChEMBL

Protein Target:: Sodium-dependent noradrenaline transporter

Assay data:123 Active, 40 Activity ≤ 1 µM, 1197 Tested

AID:: 1961848

Summary Compounds, Active Compounds, activity ≤ 1 µM PubMed Citation Related BioAssays by Target

Select item 196184715.

Binding affinity towards human SLC6A3 in an in vitro assay with cellular components measured by scintillation counting

Source:: ChEMBL

Protein Target:: Sodium-dependent dopamine transporter

Assay data:119 Active, 21 Activity ≤ 1 µM, 1213 Tested

AID:: 1961847

Summary Compounds, Active Compounds, activity ≤ 1 µM PubMed Citation Related BioAssays by Target

Select item 196184616.

Binding affinity towards human TBXA2R in an in vitro assay with cellular components measured by scintillation proximity assay

Source:: ChEMBL

Protein Target:: Thromboxane A2 receptor

Assay data:14 Active, 2 Activity ≤ 1 µM, 1022 Tested

AID:: 1961846

Summary Compounds, Active Compounds, activity ≤ 1 µM PubMed Citation Related BioAssays by Target

Select item 196184117.

Binding affinity towards human TACR1 in an in vitro assay with cellular components measured by membrane filtration

Source:: ChEMBL

Protein Target:: Substance-P receptor

Assay data:19 Active, 4 Activity ≤ 1 µM, 218 Tested

AID:: 1961841

Summary Compounds, Active Compounds, activity ≤ 1 µM PubMed Citation Related BioAssays by Target

Select item 196183718.

Binding affinity towards human SLC29A1 in an in vitro assay with cellular components measured by scintillation proximity assay

Source:: ChEMBL

Protein Target:: Equilibrative nucleoside transporter 1

Assay data:20 Active, 4 Activity ≤ 1 µM, 1115 Tested

AID:: 1961837

Summary Compounds, Active Compounds, activity ≤ 1 µM PubMed Citation Related BioAssays by Target

Select item 196182719.

Compound was evaluated for inhibition of human PTGS2 in an in vitro cell free assay measured by fluorescence spectroscopy

Source:: ChEMBL

Protein Target:: Prostaglandin G/H synthase 2

Assay data:79 Active, 12 Activity ≤ 1 µM, 1183 Tested

AID:: 1961827

Summary Compounds, Active Compounds, activity ≤ 1 µM PubMed Citation Related BioAssays by Target

Select item 196182520.

Compound was evaluated for inhibition of rat Ptgs1 in an in vitro cell free assay measured by fluorescence spectroscopy

Source:: ChEMBL

Protein Target:: Prostaglandin G/H synthase 1

Assay data:74 Active, 33 Activity ≤ 1 µM, 1201 Tested

AID:: 1961825

Summary Compounds, Active Compounds, activity ≤ 1 µM PubMed Citation Related BioAssays by Target

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Proteins (50)
BioAssays with protein sequences specified as targets

BioActivity

Active Compounds (501)
BioAssays with compounds reported as biologically active
Activity (IC50, etc) ≤ 1 nM (81)
BioAssays with the active concentration of tested reagents less than 1 nanomolar
Activity (IC50, etc) ≤ 1 µM (371)
BioAssays with the active concentration of tested reagents less than 1 micromolar

Experiment Type

Confirmatory (499)
Low-throughput BioAssays where the activity outcome is based on a dose-response relationship with multiple tested concentrations
Primary Screening (5)
Primary high-throughput BioAssays where the activity outcome is based on percentage inhibition from a single dose

Assay Project (55)
BioAssays organized into assay projects based on linkage to Summary assays. Click an project below to retrieve the bioassay list for the project. Click 'All Assay Projects' to retrieve all assay projects represented by Summary assays.

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Literature Extraction (2,505)
BioAssays extracted from the literature
NIH MLP (56)
BioAssays deposited by the NIH Molecular Libraries Program
Other (139)
BioAssays deposited by other experimentalists

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