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Antiviral activity determined as inhibition of SARS-CoV-2 induced cytotoxicity of VERO-6 cells at 10 uM after 48 hours exposure to 0.01 MOI SARS CoV-2 virus by high content imaging
Assay data:2 Activity ≤ 1 µM, 4307 Tested
SummaryCompounds, activity ≤ 1 µM
Rat beta2-adrenoceptor (Adrenoceptors)
Assay data:1 Active, 1 Tested
SummaryCompounds, ActivePubMed CitationRelated BioAssays by Target
Toxoplasma gondii HTS in the absence of IFN-y
Assay data:614 Active, 6425 Tested
SummaryCompounds, ActiveRelated BioAssays by DepositorRelated BioAssays by Target
Toxoplasma gondii inhibition HTS in the presence of IFN-y
Assay data:2597 Active, 69085 Tested
Selectivity ratio for in vivo inhibition of beta-2 adrenergic receptor in guinea pig over in vivo inhibition of beta-1 adrenergic receptor in guinea pig
Assay data:2 Tested
SummaryPubMed Citation
Selectivity ratio of antagonist activity at beta-2 adrenergic receptor in carbachol-treated guinea pig trachea to antagonist activity at beta-1 adrenergic receptor in spontaneously beating guinea pig right atrium
Assay data:56 Tested
Bronchoselectivity as antilog difference between pA2 for tracheal beta-2 and atrial beta-1 assays
Assay data:12 Tested
Selectivity index is the ratio of tracheal to atrial pA2 values
Assay data:10 Tested
Inhibition of binding of Batrachotoxinin [3H]BTX-B to high affinity sites on voltage dependent sodium channels in a vesicular preparation from guinea pig cerebral cortex at 10 uM
Assay data:161 Tested
SummaryPubMed CitationRelated BioAssays by Target
Inhibition of binding of Batrachotoxinin [3H]BTX-B to high affinity sites on voltage dependent sodium channels in a vesicular preparation from guinea pig cerebral cortex
Assay data:69 Active, 12 Activity ≤ 1 µM, 113 Tested
SummaryCompounds, ActiveCompounds, activity ≤ 1 µMPubMed CitationRelated BioAssays by Target
Antagonistic activity against beta-1 adrenergic receptor of isolated guinea pig atria
Assay data:5 Active, 1 Activity ≤ 1 µM, 12 Tested
SummaryCompounds, ActiveCompounds, activity ≤ 1 µMPubMed Citation
Antagonist activity against beta-1 adrenergic receptor in isolated guinea pig atria
Assay data:5 Active, 2 Activity ≤ 1 µM, 11 Tested
Specific antagonistic activity difference against beta-2 adrenergic receptor of isolated guinea pig tracheal strips
Antagonistic activity against beta-2 adrenergic receptor on isolated guinea pig tracheal strips
Assay data:10 Active, 10 Activity ≤ 1 µM, 11 Tested
Antagonist activity against beta-2 adrenergic receptor in isolated guinea pig trachea
Assay data:7 Active, 3 Activity ≤ 1 µM, 10 Tested
Antagonistic activity against beta-2 adrenergic receptor of isolated guinea pig tracheal strips
Specific antagonistic activity difference against beta-1 adrenergic receptor of isolated guinea pig atria
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