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Cytotoxicity against human Megakaryocyte cells assessed as inhibition of colony growth by measuring colony forming units
Assay data:29 Active, 26 Activity ≤ 1 µM, 29 Tested
SummaryCompounds, ActiveCompounds, activity ≤ 1 µMPubMed Citation
Antiproliferative activity against human NCI-H23 cells assessed as cell growth inhibition measured after 7 days by alamar blue assay
Assay data:24 Active, 22 Activity ≤ 1 µM, 24 Tested
Antiproliferative activity against human A-427 cells assessed as cell growth inhibition measured after 7 days by alamar blue assay
Assay data:29 Active, 27 Activity ≤ 1 µM, 29 Tested
Inhibition of WEE1 in human U2OS cells incubated for 1 hr by mesoscale discovery assay
Assay data:42 Active, 36 Activity ≤ 1 µM, 42 Tested
SummaryCompounds, ActiveCompounds, activity ≤ 1 µMPubMed CitationRelated BioAssays by Target
Inhibition of human full length GST-tagged WEE1 expressed in insect cells incubated for 15 mins followed by ATP addition by ADP Glo luminescent assay
Assay data:49 Active, 47 Activity ≤ 1 µM, 49 Tested
Inhibition of human N-terminal His6-tagged recombinant full-length PLK1 expressed in baculovirus infected Sf9 cells incubated for 15 mins followed by ATP addition by ADP Glo luminescent assay
Assay data:33 Active, 10 Activity ≤ 1 µM, 49 Tested
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