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Anti-tumor activity against human PDX CR6256 cells xenografted with nude BALB/c mouse assessed as inhibition of tumor growth inhibition at 30 mg/kg, po QD for 21 days co-treated with 20 mg/kg, ip QD Cetuximab relative to control
Assay data:1 Tested
SummaryPubMed Citation
Anti-tumor activity against human NCI-H2122 cells xenografted with nude mouse assessed as inhibition of tumor growth inhibition at 50 mg/kg, po QD for 21 days co-treated with 50 mg/kg, po QD Erlotinib relative to control
Anti-tumor activity against human NCI-H2122 cells xenografted with nude mouse assessed as inhibition of tumor growth inhibition at 50 mg/kg, po QD for 21 days relative to control
Assay data:2 Tested
Homogeneous Time Resolved Fluorescence (HTRF) Assay from US Patent US11236068: "Fused ring compounds"
Assay data:97 Active, 88 Activity ≤ 1 µM, 99 Tested
SummaryCompounds, ActiveCompounds, activity ≤ 1 µMRelated BioAssays by Target
NCI human tumor cell line growth inhibition assay. Data for the SN12C Renal cell line
Assay data:3204 Active, 55031 Tested
SummaryCompounds, ActivePubMed CitationRelated BioAssays by Depositor
NCI human tumor cell line growth inhibition assay. Data for the UO-31 Renal cell line
Assay data:3125 Active, 54781 Tested
NCI human tumor cell line growth inhibition assay. Data for the TK-10 Renal cell line
Assay data:2149 Active, 54007 Tested
NCI human tumor cell line growth inhibition assay. Data for the ACHN Renal cell line
Assay data:3434 Active, 54892 Tested
NCI human tumor cell line growth inhibition assay. Data for the 786-0 Renal cell line
Assay data:3282 Active, 54398 Tested
NCI human tumor cell line growth inhibition assay. Data for the RXF 393 Renal cell line
Assay data:3628 Active, 49866 Tested
NCI human tumor cell line growth inhibition assay. Data for the CAKI-1 Renal cell line
Assay data:3482 Active, 52108 Tested
NCI human tumor cell line growth inhibition assay. Data for the A498 Renal cell line
Assay data:3670 Active, 48923 Tested
NCI human tumor cell line growth inhibition assay. Data for the HL-60(TB) Leukemia cell line
Assay data:5041 Active, 50324 Tested
NCI human tumor cell line growth inhibition assay. Data for the MOLT-4 Leukemia cell line
Assay data:4563 Active, 54231 Tested
NCI human tumor cell line growth inhibition assay. Data for the K-562 Leukemia cell line
Assay data:4962 Active, 53821 Tested
NCI human tumor cell line growth inhibition assay. Data for the CCRF-CEM Leukemia cell line
Assay data:5336 Active, 52551 Tested
NCI human tumor cell line growth inhibition assay. Data for the SR Leukemia cell line
Assay data:5652 Active, 45957 Tested
NCI human tumor cell line growth inhibition assay. Data for the RPMI-8226 Leukemia cell line
Assay data:4446 Active, 51631 Tested
NCI human tumor cell line growth inhibition assay. Data for the OVCAR-8 Ovarian cell line
Assay data:3317 Active, 55489 Tested
NCI human tumor cell line growth inhibition assay. Data for the OVCAR-5 Ovarian cell line
Assay data:2276 Active, 54490 Tested
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