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Activation of T1R1/T1R3 Receptor by Nucleotide Derivatives (alanine) from US Patent US11185100: "Methods for modulating taste receptors"
Assay data:5 Active, 3 Activity ≤ 1 µM, 50 Tested
SummaryCompounds, ActiveCompounds, activity ≤ 1 µMRelated BioAssays by DepositorRelated BioAssays by Target
Antiviral activity determined as inhibition of SARS-CoV-2 induced cytotoxicity of VERO-6 cells at 10 uM after 48 hours exposure to 0.01 MOI SARS CoV-2 virus by high content imaging
Assay data:2 Activity ≤ 1 µM, 4309 Tested
SummaryCompounds, activity ≤ 1 µM
Activation of human T1R2/T1R3
Assay data:1 Tested
SummaryRelated BioAssays by Target
Inhibition of Escherichia coli HGPRT
Assay data:2 Tested
SummaryPubMed Citation
Inhibition of human HGPRT
Assay data:9 Active, 5 Activity ≤ 1 µM, 9 Tested
SummaryCompounds, ActiveCompounds, activity ≤ 1 µMPubMed CitationRelated BioAssays by Target
Inhibition of Mycobacterium tuberculosis HGPRT
Experimentally measured binding affinity data (Kd) for protein-ligand complexes derived from PDB
Assay data:3916 Active, 206 Activity ≤ 1 nM, 1830 Activity ≤ 1 µM, 3916 Tested
SummaryCompounds, ActiveCompounds, activity ≤ 1 µMPubMed CitationRelated BioAssays by DepositorRelated BioAssays by Target
Experimentally measured binding affinity data (Ki) for protein-ligand complexes derived from PDB
Assay data:3598 Active, 421 Activity ≤ 1 nM, 2233 Activity ≤ 1 µM, 3598 Tested
Binding affinity to Escherichia coli HPRT
Inhibitory activity against Inosine-5'-monophosphate dehydrogenase
Assay data:1 Active, 1 Activity ≤ 1 µM, 1 Tested
Ability to inhibit Inosine-5'-monophosphate dehydrogenase isolated from Escherichia coli
SummaryPubMed CitationRelated BioAssays by Target
Inhibition of inosine monophosphate dehydrogenase in Escherichia coli
Experimentally measured binding affinity data derived from PDB
Assay data:3073 Active, 3073 Tested
SummaryCompounds, ActivePubMed CitationRelated BioAssays by Target
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