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ERα TR-FRET Test from US Patent US20240217988: "ESTROGEN RECEPTOR ANTAGONIST"
Assay data:14 Active, 14 Activity ≤ 1 µM, 14 Tested
SummaryCompounds, ActiveCompounds, activity ≤ 1 µMRelated BioAssays by Target
Evaluation of A2a Receptor Binding Affinity from US Patent US20240217978: "COMPOUND AS ADENOSINE A2a RECEPTOR ANTAGONIST AND PHARMACEUTICAL COMPOSITION COMPRISING SAME"
Assay data:395 Active, 50 Activity ≤ 1 nM, 388 Activity ≤ 1 µM, 396 Tested
hERG Inhibition Assay from US Patent US20240216357: "POLYCYCLIC COMPOUND AND APPLICATION THEREOF"
Assay data:23 Active, 41 Tested
SummaryCompounds, ActiveRelated BioAssays by DepositorRelated BioAssays by Target
Receptor Binding Assay from US Patent US12023331: "Methods"
Assay data:2 Active, 2 Activity ≤ 1 µM, 2 Tested
hERG Qpatch Assay from US Patent US20240208953: ""Cyclopenta[c]pyrrol Negative Allosteric Modulators of NR2B""
Assay data:20 Active, 4 Activity ≤ 1 µM, 25 Tested
Binding assay NK-1 from US Patent US20240199618: "NOVEL N-ACYL-[3-SUBSTITUTED]-[8-SUBSTITUTED]-5,6-DIHYDRO-[1,2,4]TRIAZOLO[4,3-a]PYRAZINES AS SELECTIVE NK-3 RECEPTOR ANTAGONISTS, PHARMACEUTICAL COMPOSITION, METHODS FOR USE IN NK-3 RECEPTOR-MEDIATED DISORDERS"
Assay data:42 Tested
SummaryRelated BioAssays by DepositorRelated BioAssays by Target
Binding Competition Assay with Human NK-3 Receptor from US Patent US20240199618: "NOVEL N-ACYL-[3-SUBSTITUTED]-[8-SUBSTITUTED]-5,6-DIHYDRO-[1,2,4]TRIAZOLO[4,3-a]PYRAZINES AS SELECTIVE NK-3 RECEPTOR ANTAGONISTS, PHARMACEUTICAL COMPOSITION, METHODS FOR USE IN NK-3 RECEPTOR-MEDIATED DISORDERS"
Assay data:45 Active, 45 Activity ≤ 1 µM, 45 Tested
SummaryCompounds, ActiveCompounds, activity ≤ 1 µMRelated BioAssays by DepositorRelated BioAssays by Target
hERG Qpatch Assay Protocol from US Patent US20240199576: "NOVEL CYCLOPENTA[C]PYRROL NEGATIVE ALLOSTERIC MODULATORS OF NR2B"
Assay data:3 Active, 5 Tested
SummaryCompounds, ActiveRelated BioAssays by Target
hEP4 cAMP Assay from US Patent US12011444: "N-substituted indole derivatives as PGE2 receptor modulators"
Assay data:1074 Active, 7 Activity ≤ 1 nM, 1074 Activity ≤ 1 µM, 1074 Tested
[3H]Dopamine ([3H]DA) Uptake Assay from US Patent US11999676: "Vesicular monoamine transporter-2 ligands and their use in the treatment of psychostimulant abuse"
Assay data:47 Active, 47 Activity ≤ 1 µM, 47 Tested
[3H]Dihydrotetrabenazine ([3H]DTBZ) Binding Assay from US Patent US11999676: "Vesicular monoamine transporter-2 ligands and their use in the treatment of psychostimulant abuse"
Assay data:49 Active, 18 Activity ≤ 1 µM, 53 Tested
[3H]DA and [3H]5-HT Uptake Assay from US Patent US11999676: "Vesicular monoamine transporter-2 ligands and their use in the treatment of psychostimulant abuse"
Assay data:90 Active, 90 Activity ≤ 1 µM, 91 Tested
Binding at Human Serotonin Receptors Competition Binding in Human 5-HT1B Receptor Assay from US Patent US20240166639: "POTENT AND SELECTIVE COMPOUNDS AS SEROTONIN 1B RECEPTOR MODULATORS"
Assay data:17 Active, 4 Activity ≤ 1 nM, 16 Activity ≤ 1 µM, 17 Tested
Inhibition of PDE4 from US Patent US11987556: "Dual-functional compounds and methods of use"
Assay data:6 Active, 6 Activity ≤ 1 µM, 6 Tested
MT1/MT2 Receptor Binding Assay from US Patent US11980598: "N-(2-(substituted-naphth-1-yl)ethyl) substituted amide compound, preparation and uses thereof"
Assay data:3 Active, 3 Activity ≤ 1 nM, 3 Activity ≤ 1 µM, 3 Tested
Inhibition Assays of Transporters (hSERT and rVMAT2) from US Patent US20240150372: "OXA-IBOGAINE ANALOGUES FOR TREATMENT OF SUBSTANCE USE DISORDERS"
Assay data:3 Active, 2 Activity ≤ 1 µM, 3 Tested
hERG Channel Inhibitory Activity Assay from US Patent US20240150370: "BICYCLIC PYRIDINE DERIVATIVE"
Assay data:2 Active, 39 Tested
Adenosine Receptor Activity Assay from US Patent US11974991: "Adenosine receptor activity of methyl/ethyl 3-(substituted benzoyl)-6,8-dimethylindolizine-2-substituted-1-carboxylates"
Assay data:11 Active, 5 Activity ≤ 1 µM, 13 Tested
Affinity of the Compounds of the Present Invention for Dopamine D2 Receptors from US Patent US20240124456: "AZA-ERGOLINE DERIVATIVE AND PREPARATION METHOD THEREFOR AND APPLICATION THEREOF"
Assay data:32 Active, 1 Activity ≤ 1 nM, 29 Activity ≤ 1 µM, 32 Tested
hERG Assay from US Patent US11970463: "Compounds and their use"
Assay data:1 Active, 35 Tested
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