Warning: The NCBI web site requires JavaScript to function. more...
An official website of the United States government
The .gov means it's official. Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you're on a federal government site.
The site is secure. The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.
Inhibition of human recombinant ADAM10 expressed in baculovorus-infected Sf21 cells using Mca-Lys-Pro-Leu-Gly-Leu-Dap(Dnp)-Ala-Arg-NH2 as substrate preincubated with enzyme for 1 hr followed by substrate addition and measured every 10 secs for 15 mins by fluorescence based analysis
Assay data:2 Active, 1 Activity ≤ 1 µM, 4 Tested
SummaryCompounds, ActiveCompounds, activity ≤ 1 µMPubMed CitationRelated BioAssays by Target
Inhibition of human ADAM10 using (biotin-SPLAQAVRSSSRTP(3H)S-NH2) as a substrate by streptavidin-coated scintillation proximity assay
Assay data:1 Active, 1 Activity ≤ 1 µM, 1 Tested
Inhibition of human ADAM10 using (7-methoxycour-marin-4-yl)-acetyl-Pro-Leu-Ala-Gln-Ala-Val-(3-[2,4-dinitrophenyl]- L -2, 3-diaminopropionyl)-Arg-Ser-Ser-Ser-Arg-NH2 as a substrate
Inhibition Assay from US Patent US9365529: "Benzenesulfonamide compounds, method for synthesizing same, and use thereof in medicine as well as in cosmetics"
Assay data:9 Active, 4 Activity ≤ 1 µM, 9 Tested
SummaryCompounds, ActiveCompounds, activity ≤ 1 µMRelated BioAssays by DepositorRelated BioAssays by Target
Inhibition Assay from US Patent US9266848: "4-alkoxy-N-(2-hydroxycarbamoyl-2-piperidinyl-ethyl)-benzamide compounds as selective TACE-inhibitors for the treatment of inflammatory diseases"
Assay data:3 Active, 1 Activity ≤ 1 µM, 5 Tested
Enzyme Assay from US Patent US9115102: "N-[2-hydroxycarbamoyl-2-(piperazinyl) ethyl] benzamide compounds, their preparation and their use as TACE inhibitors"
Assay data:4 Active, 4 Activity ≤ 1 µM, 4 Tested
Enzymatic Assay from US Patent US8772478: "Benzenesulfonamide compounds, method for synthesizing same, and use thereof in medicine as well as in cosmetics"
Assay data:9 Active, 9 Activity ≤ 1 µM, 9 Tested
SummaryCompounds, ActiveCompounds, activity ≤ 1 µMRelated BioAssays by Target
Inhibition of ADAM-10 (unknown origin)
Assay data:2 Tested
SummaryPubMed CitationRelated BioAssays by Target
Inhibition of ADAM10 (unknown origin) assessed as blockage of TNF-alpha shedding
Inhibition of ADAM10 (unknown origin)
Inhibition of recombinant human C-terminal His10-tagged ADAM10 expressed in baculovirus infected Sf21 cells at 200 uM using Abz-LANAVRSSSR-(DapDnp)-NH2 as substrate by fluorescence assay
Assay data:1 Tested
Inhibition of recombinant human C-terminal His10-tagged ADAM10 expressed in baculovirus infected Sf21 cells using Abz-LANAVRSSSR-(DapDnp)-NH2 as substrate by fluorescence assay
Inhibition of ADAM10 (unknown origin) at 1 uM relative to control
Inhibition of human recombinant ADAM10 at 100 uM using Mca-Lys-Pro-Leu-Gly-Leu-Dpa-Ala-Arg-NH2 substrate
Assay data:3 Tested
Inhibition of human ADAM10 assessed as residual activity using Abz-LANAVRSSSR-(DapDnp)-AR-NH2 as substrate at 200 uM by fluorescence assay relative to control
Assay data:6 Tested
Assay data:2 Active, 1 Activity ≤ 1 µM, 2 Tested
Inhibition of recombinant human C-terminal His10-tagged ADAM10 (Thr214 to Glu672 residues) expressed in baculovirus infected Sf21 cells using McaKPLGL-Dpa-AR-NH2 as substrate by fluorescence spectrophotometric method
Inhibition of recombinant human C-terminal His10-tagged ADAM10 (Thr214 to Glu672 residues) expressed in baculovirus infected Sf21 cells at 10 uM using McaKPLGL-Dpa-AR-NH2 as substrate by fluorescence spectrophotometric method relative to control
Human ADAM10 (M12: Astacin/Adamalysin)
Assay data:3 Active, 3 Tested
SummaryCompounds, ActivePubMed CitationRelated BioAssays by Target
Filters: Manage Filters
Your browsing activity is empty.
Activity recording is turned off.
Turn recording back on