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IL-1 Secretion Assa from US Patent US11208399: "NLRP3 inflammasome inhibitors"
Assay data:117 Active, 10 Activity ≤ 1 nM, 116 Activity ≤ 1 µM, 117 Tested
SummaryCompounds, ActiveCompounds, activity ≤ 1 µMRelated BioAssays by DepositorRelated BioAssays by Target
IL-1beta Release Assay from US Patent US10676433: "Indole derivatives and their use in neurodegenerative diseases"
Assay data:143 Active, 158 Activity ≤ 1 µM, 158 Tested
IL-1beta release assay from US Patent US10323000: "Indole derivatives and their use in neurodegenerative diseases"
Assay data:142 Active, 142 Activity ≤ 1 µM, 157 Tested
cytomteric bead array (CBA) assay from US Patent US9694015: "Methods for the treatment of locally advanced breast cancer"
Assay data:9 Active, 5 Activity ≤ 1 nM, 9 Activity ≤ 1 µM, 10 Tested
SummaryCompounds, ActiveCompounds, activity ≤ 1 µMRelated BioAssays by Target
Interleukin-1beta CEREP ligand profiling
Assay data:1 Tested
SummaryRelated BioAssays by Target
Inhibition of IL1-beta (unknown origin)
Assay data:1 Active, 1 Tested
SummaryCompounds, ActivePubMed CitationRelated BioAssays by Target
qHTS for Inflammasome Signaling Inhibitors: IL-1-beta AlphaLISA screen against the NCATS CANVASS Library
Assay data:48 Active, 347 Tested
SummaryCompounds, ActivePubMed CitationRelated BioAssays by DepositorRelated BioAssays by Target
Development of inhibitors for mGluR7 (Eurofin Panel Assay Results)
SummaryCompounds, ActiveRelated BioAssays by Target
Development of inhibitors for Menin-MLL Receptor(Eurofin Panel Assay Results)
Development of inhibitors for mGluR7/8 (Eurofin Panel Assay Results)
Development of inhibitors for PLD2 (Eurofin Panel Assay Results)
SummaryCompounds, ActiveRelated BioAssays by DepositorRelated BioAssays by Same ProjectRelated BioAssays by Target
Development of inhibitors for Dopamine D4 Receptors: Eurofin Panel Assay Results
qHTS for Inhibitors of Inflammasome Signaling: IL-1-beta AlphaLISA Primary Screen
Assay data:17206 Active, 362359 Tested
SummaryCompounds, ActivePubMed CitationRelated BioAssays by DepositorRelated BioAssays by Same ProjectRelated BioAssays by Target
Development of the first CNS penetrant Muscarinic 5 (M5) Positive Allosteric Modulator based on a novel non-isatin core
SummaryRelated BioAssays by DepositorRelated BioAssays by Same ProjectRelated BioAssays by Target
Development of a novel orthosteric Muscarinic 5 (M5) antagonist possessing a hig degree of muscarinic subtype selectivity
Discovery and characterization of a small molecule allosteric agonists of mas-related G-Protein coupled receptor X1 ( MrgX1)
Development of the First Potent, Selective and CNS penetrant M5 Negative Allosteric Modulator (NAM)
ML353 Eurofin Panel Assay for mGlu5 SAM Inhibitor (Probe Compound)
ML354 Eurofin Panel Assay for PAR4 Antagonists Inhibitor (Probe Compound)
ML352 Eurofin Panel Assay for Choline Transporter Inhibitor (Probe Compound)
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