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Agonist activity at CqsS C170A mutant in Vibrio cholerae WN1982 harboring deltacqsA, deltaluxQ after 4 hrs by bioluminescence assay
Assay data:7 Active, 6 Activity ≤ 1 µM, 8 Tested
SummaryCompounds, ActiveCompounds, activity ≤ 1 µMPubMed CitationRelated BioAssays by Target
Agonist activity at CqsS C170A mutant in Vibrio cholerae WN1982 harboring deltacqsA, deltaluxQ after 4 hrs by bioluminescence assay relative to CAI-1
Assay data:7 Tested
SummaryPubMed CitationRelated BioAssays by Target
Agonist activity at CqsS C170A mutant in Vibrio cholerae WN1982 harboring deltacqsA, deltaluxQ at 50000 nM after 4 hrs by bioluminescence assay relative to CAI-1
Assay data:1 Tested
Agonist activity at CqsS C170Y mutant in Vibrio cholerae WN1977 harboring deltacqsA, deltaluxQ after 4 hrs by bioluminescence assay
Assay data:3 Active, 3 Activity ≤ 1 µM, 8 Tested
Agonist activity at CqsS C170Y mutant in Vibrio cholerae WN1977 harboring deltacqsA, deltaluxQ after 4 hrs by bioluminescence assay relative to CAI-1
Assay data:4 Tested
Agonist activity at CqsS C170Y mutant in Vibrio cholerae WN1977 harboring deltacqsA, deltaluxQ at 50000 nM after 4 hrs by bioluminescence assay relative to CAI-1
CqsS In vitro Kinase Assay Measured in Biochemical System Using Imaging - 2132-10_Agonist_Dose_DryPowder_Activity
Assay data:3 Active, 3 Tested
SummaryCompounds, ActivePubMed CitationRelated BioAssays by DepositorRelated BioAssays by Same ProjectRelated BioAssays by Target
Cholera Quorum: HTS for inducers of light production in the absence of autoinducers using BH1578 (luxS deficient, cqsA deficient) Measured in Microorganism System Using Plate Reader - 2132-01_Agonist_Dose_DryPowder_Activity_Set2
Assay data:5 Active, 4 Activity ≤ 1 µM, 51 Tested
SummaryCompounds, ActiveCompounds, activity ≤ 1 µMPubMed CitationRelated BioAssays by DepositorRelated BioAssays by Same ProjectRelated BioAssays by Target
Quorum LuxO: Assay for inducers of light production in the absence of autoinducers using BH1651 (luxOD47E) Measured in Microorganism System Using Plate Reader - 2132-03_Agonist_Dose_DryPowder_Activity_Set3
Assay data:1 Active, 45 Tested
Ratio of compound IC50 to Ph-CAI-1 IC50 for CqsS receptor in Vibrio cholerae MM920 assessed as inhibition of quorum sensing regulated CAI-1 induced bioluminescence after 4 hrs by scintillation counting
Assay data:26 Tested
Antagonist activity at CqsS receptor in Vibrio cholerae MM920 assessed as inhibition of quorum sensing regulated CAI-1 induced bioluminescence after 4 hrs by scintillation counting relative to Ph-CAI-1
Assay data:13 Tested
Antagonist activity at CqsS receptor in Vibrio cholerae MM920 assessed as inhibition of quorum sensing regulated CAI-1 induced bioluminescence after 4 hrs by scintillation counting
Ratio of compound EC50 to (S)-CAI-1 EC50 for CqsS receptor in cqsA-deficient, luxQ-deficient Vibrio cholerae MM920 harboring cosmid pBB1 carrying Vibrio harveyi luxCDABE gene assessed as induction of quorum sensing regulated bioluminescence after 4 hrs by scintillation counting
Assay data:24 Tested
Agonist activity at CqsS receptor in cqsA-deficient, luxQ-deficient Vibrio cholerae MM920 harboring cosmid pBB1 carrying Vibrio harveyi luxCDABE gene assessed as quorum sensing regulated bioluminescence after 4 hrs by scintillation counting relative to (S)-CAI-1
Assay data:17 Tested
Agonist activity at CqsS receptor in cqsA-deficient, luxQ-deficient Vibrio cholerae MM920 harboring cosmid pBB1 carrying Vibrio harveyi luxCDABE gene assessed as induction of quorum sensing regulated bioluminescence after 4 hrs by scintillation counting
Assay data:15 Active, 5 Activity ≤ 1 µM, 25 Tested
Agonist activity at CqsS receptor in cqsA-deficient, luxQ-deficient Vibrio cholerae MM920 harboring cosmid pBB1 carrying Vibrio harveyi luxCDABE gene assessed as maximal quorum sensing regulated bioluminescence at 50 uM after 4 hrs by scintillation counting relative to (S)-CAI-1
Assay data:3 Tested
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