Warning: The NCBI web site requires JavaScript to function. more...
An official website of the United States government
The .gov means it's official. Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you're on a federal government site.
The site is secure. The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.
Fluorescence Polarization Assay from US Patent US12030867: "Hsp90β selective inhibitors"
Assay data:17 Active, 15 Activity ≤ 1 µM, 18 Tested
SummaryCompounds, ActiveCompounds, activity ≤ 1 µMRelated BioAssays by Target
Binding affinity to HSP90 (unknown origin)
Assay data:2 Active, 2 Activity ≤ 1 µM, 2 Tested
SummaryCompounds, ActiveCompounds, activity ≤ 1 µMPubMed CitationRelated BioAssays by Target
Binding affinity to full length HSP90 (unknown origin) expressed in Escherichia coli BL21(DE3) cells at 20 uM by NMR STD assay
Assay data:1 Active, 1 Tested
SummaryCompounds, ActivePubMed CitationRelated BioAssays by Target
Inhibition of HSP90 in human HL-60 cells assessed as decrease in CDK4 protein expression incubated for 24 hrs by western blot analysis
Assay data:2 Tested
SummaryPubMed CitationRelated BioAssays by Target
Inhibition of HSP90 in human HL-60 cells assessed as increase in HSP27 protein expression incubated for 24 hrs by western blot analysis
Inhibition of HSP90 (unknown origin)
Assay data:1 Active, 1 Activity ≤ 1 µM, 3 Tested
Inhibition of HSP90alpha in human NCI-H522 cells assessed as decrease in CDK4 level at 10 to 80 uM incubated for 24 hrs by Western blot analysis
Assay data:2 Active, 2 Tested
Inhibition of HSP90alpha in human SK-OV-3 cells assessed as decrease in CDK4 level at 10 to 80 uM incubated for 24 hrs by Western blot analysis
Inhibition of HSP90alpha in human SK-OV-3 cells assessed as decrease in p-Src level at 10 to 80 uM incubated for 24 hrs by Western blot analysis
Inhibition of HSP90alpha in human SK-OV-3 cells assessed as decrease in p-Akt level at 10 to 80 uM incubated for 24 hrs by Western blot analysis
Inhibition of HSP90alpha in human SK-OV-3 cells assessed as decrease in c-Src protein level incubated for 24 hrs by Western blot analysis
Inhibition of HSP90alpha in human SK-OV-3 cells assessed as decrease in survivin protein level incubated for 24 hrs by Western blot analysis
Inhibition of HSP90alpha in human SK-OV-3 cells assessed as decrease in Akt protein level incubated for 24 hrs by Western blot analysis
Inhibition of HSP90alpha in human SK-OV-3 cells assessed as decrease in Raf-1 protein level incubated for 24 hrs by Western blot analysis
Inhibition of HSP90alpha in human SK-OV-3 cells assessed as decrease in Her2 protein level incubated for 24 hrs by Western blot analysis
Inhibition of HSP90alpha in human NCI-H522 cells assessed as decrease in c-Src protein level incubated for 24 hrs by Western blot analysis
Inhibition of HSP90alpha in human NCI-H522 cells assessed as decrease in survivin protein level incubated for 24 hrs by Western blot analysis
Inhibition of HSP90alpha in human NCI-H522 cells assessed as decrease in Akt protein level incubated for 24 hrs by Western blot analysis
Inhibition of HSP90alpha in human NCI-H522 cells assessed as decrease in Raf-1 protein level incubated for 24 hrs by Western blot analysis
Inhibition of HSP90alpha in human NCI-H522 cells assessed as decrease in Her2 protein level incubated for 24 hrs by Western blot analysis
Filters: Manage Filters
Your browsing activity is empty.
Activity recording is turned off.
Turn recording back on