Warning: The NCBI web site requires JavaScript to function. more...
An official website of the United States government
The .gov means it's official. Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you're on a federal government site.
The site is secure. The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.
Drug level assessed as Acinetobacter baumannii ADC-1-mediated compound formation treated with (6R,7R)-3-((((2-(4-(4-((S)-5-(Acetamidomethyl)-2-oxooxazolidin-3-yl)-2-fluorophenyl)piperazin-1-yl)-2-oxoethyl)-carbamoyl)oxy)methyl)-7-(2-(2-(N-(4-(2,3-dihydroxybenzamido)butyl)-2,3-dihydroxybenzamido)acetamido)-2-phenylacetamido)-8-oxo-5-thia-1-azabicyclo[4.2.]oct-2-ene-2-caboxylic acid at 20 uM after 40 mins by LC/MS method
Assay data:1 Tested
SummaryPubMed CitationRelated BioAssays by Target
Drug metabolism assessed as Acinetobacter baumannii ADC-1-mediated (S)-N-((3-(3-Fluoro-4-(4-glycylpiperazin-1-yl)phenyl)-2-oxooxazolidin-5-yl)methyl)acetamide release at 20 uM after 40 mins by LC/MS method
Inhibition of Acinetobacter genomosp. 3 isolate 195 ADC-18
Assay data:2 Tested
Inhibition of Acinetobacter genomosp. 3 isolate 103 ADC-16
Assay data:1 Active, 2 Tested
SummaryCompounds, ActivePubMed CitationRelated BioAssays by Target
Inhibition of Acinetobacter genomosp. 3 isolate 65 ADC-14
Ratio of Kcat to Km for Acinetobacter genomosp. 3 isolate 195 ADC-18
Assay data:7 Tested
Activity of Acinetobacter genomosp. 3 isolate 195 ADC-18
Assay data:6 Active, 3 Activity ≤ 1 µM, 8 Tested
SummaryCompounds, ActiveCompounds, activity ≤ 1 µMPubMed CitationRelated BioAssays by Target
Ratio of Kcat to Km for Acinetobacter genomosp. 3 isolate 103 ADC-16
Activity of Acinetobacter genomosp. 3 isolate 103 ADC-16
Ratio of Kcat to Km for Acinetobacter genomosp. 3 isolate 65 ADC-14
Activity of Acinetobacter genomosp. 3 isolate 65 ADC-14
Assay data:7 Active, 4 Activity ≤ 1 µM, 8 Tested
Filters: Manage Filters
Your browsing activity is empty.
Activity recording is turned off.
Turn recording back on