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Competitive binding affinity to human annexin A2 in human A549 cell lysate at 10 uM for 30 mins followed by GOYA-P treatment for 30 mins by DTB-Cy3 dye based SDS-PAGE analysis
Assay data:2 Active, 2 Tested
SummaryCompounds, ActivePubMed CitationRelated BioAssays by Target
Inhibition of human ANXA2/S100A10 interaction in MDA-MB-231 cells at 5 to 10 uM measured after 48 hrs by immunocytochemistry assay
Assay data:1 Active, 1 Tested
Binding affinity to human ANXA2 in human MDA-MB-231 cell lysate by western blot analysis
Assay data:1 Active, 2 Tested
Inhibition of human ANXA2/S100A10 interaction in MDA-MB-231 cells pretreated with compound for 48 hrs by immunoprecipitation based Western blot analysis
Binding affinity to putative annexin A2-like protein in human Hela cells lysates assessed as protein enrichment by measuring normalized heavy/light ratio at by nano-LC-ESIMS/MS analysis
Assay data:1 Tested
SummaryPubMed CitationRelated BioAssays by Target
Inhibition of Annexin A2/Protein S100-A10 (unknown origin) protein interaction by competitive fluorescent binding assay
SummaryRelated BioAssays by Target
Inhibition of Annexin A2/Protein S100-A10 protein interaction in human MDA-MB-231 cells by Western blotting based immunoprecipitation assay
Inhibition of Annexin A2 N-terminus/Protein S100-A10 (unknown origin) protein interaction pre-incubated for 5 mins by FRET assay
Assay data:12 Active, 36 Tested
Inhibition of annexin A2-S100A10 interaction in human MDA-MB-231 cells at 10 to 100 uM after 10 mins by broken cell immunoprecipitation assay
Inhibition of annexin A2-S100A10 interaction in human MDA-MB-231 cell lysates at 50 uM after 10 mins by Western blotting
Inhibition of annexin A2-S100A10 interaction in human MDA-MB-231 cell lysates at 50 uM after 10 mins by Western blotting relative to control
Assay data:2 Tested
Inhibition of Cy3-labeled annexin A2(1-14)-Cy5- labeled S100A10 interaction at 50 uM after 5 mins by counterscreen assay relative to control
Assay data:22 Tested
Inhibition of Cy3-labeled annexin A2(1-14)-Cy5- labeled S100A10 interaction after 5 mins by counterscreen assay
Assay data:15 Active, 42 Tested
Inhibition of Cy3-labeled annexin A2(1-14)-Cy5- labeled S100A10 interaction after 5 mins by FRET assay
Assay data:3 Active, 13 Tested
Displacement of biotinyl-withaferin from annexin-2 in human CHP100 at 0.4 to 4 uM by chemiluminescence assay
Displacement of biotinyl-withaferin from annexin-2 in human MCF10A at 0.4 to 4 uM by chemiluminescence assay
Induction of annexin 2-mediated cytoskeleton aggregate accumulation in human HepG2 cells at 4 uM after 2 hrs by confocal laser scanning microscopy
Induction of annexin 2-mediated F-actin disruption in human HepG2 cells at 4 uM after 2 hrs by confocal laser scanning microscopy
Induction of annexin 2-mediated F-actin disruption in human WI38 cells at 4 uM after 2 hrs by confocal laser scanning microscopy
Effect on human annexin 2-mediated F-actin bundling assessed as increase in light scattering after 1 hr by SDS-PAGE
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