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Purinergic P2Y Eurofins Panlabs panel
Assay data:1 Tested
SummaryRelated BioAssays by Target
Antagonist activity at human P2Y6
Assay data:2 Active, 2 Activity ≤ 1 µM, 2 Tested
SummaryCompounds, ActiveCompounds, activity ≤ 1 µMPubMed CitationRelated BioAssays by Target
Antagonist activity at P2Y6 (unknown origin)
Assay data:1 Active, 1 Activity ≤ 1 µM, 1 Tested
Binding affinity to human P2Y6R expressed in CHO cells at upto 10 uM by competitive binding method
Assay data:4 Tested
SummaryPubMed CitationRelated BioAssays by Target
Antagonist activity at human P2Y6R expressed in human 1321N1 cells assessed as inhibition of UDP-induced calcium mobilization at 100 uM by FLIPR assay relative to control
Assay data:3 Tested
Antagonist activity at human P2Y6R expressed in human 1321N1 cells assessed as inhibition of UDP-induced calcium mobilization incubated for 5 mins followed by agonist stimulation by FLIPR assay
Assay data:2 Active, 1 Activity ≤ 1 µM, 2 Tested
Antagonist activity at human P2Y6R expressed in human 1321N1 cells assessed as inhibition of UDP-induced calcium mobilization by FLIPR assay
Assay data:17 Active, 1 Activity ≤ 1 µM, 21 Tested
Antagonist activity at P2Y6R (unknown origin) expressed in human 1321N1 cells assessed as inhibition of forskolin-stimulated cAMP accumulation incubated for 15 mins in presence of IBMX by chromatography
Antagonist activity at human P2Y6R expressed in HEK293 cells assessed as inhibition of UDP-induced IP3 production preincubated for 0.5 hrs followed by UDP stimulation by ELISA
Purinergic P2Y Eurofins-Panlabs radioligand binding assay
Assay data:9 Tested
PRESTO-Tango GPCRome screening (P2RY6)
P2Y CEREP ligand profiling
P2Y-purinergic receptor CEREP ligand profiling
P2Y Ligand binding assay
Agonist activity at human P2Y6R expressed in 1321N1 cells at 3 uM measured after 30 mins by scintillation proximity assay relative to control
Assay data:2 Tested
Agonist activity at human P2Y6R expressed in 1321N1 cells assessed as calcium mobilization measured by FLIPR method
Assay data:7 Active, 4 Activity ≤ 1 µM, 7 Tested
Agonist activity at at human P2Y6R expressed in 1321N1 cells assessed as calcium mobilization at 3 uM measured by microplate reader method relative to control
Assay data:10 Tested
Agonist activity at human P2Y6R expressed in 1321N1 cells measured after 30 mins by scintillation proximity assay
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