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hERG Inhibition Assay from US Patent US20240254124: "AZAINDOLE ROCK INHIBITORS"
Assay data:1 Active, 1 Activity ≤ 1 µM, 3 Tested
SummaryRelated BioAssays by DepositorRelated BioAssays by Target
IonWorks Quattro Assay for hERG and nav1.5 from US Patent US20240190854: "PYRIMIDINE OR PYRIDINE DERIVATIVES USEFUL AS HCN2 MODULATORS"
Assay data:52 Active, 5 Activity ≤ 1 µM, 58 Tested
Sophion Qube Assay for HCN1, HCN2, HCN4, hERG, and nav1.5 from US Patent US20240190854: "PYRIMIDINE OR PYRIDINE DERIVATIVES USEFUL AS HCN2 MODULATORS"
Assay data:18 Active, 4 Activity ≤ 1 µM, 20 Tested
TREK-1 Manual Patch Clamp (hMPC) assay from US Patent US20240190824: "INHIBITORS OF TREK (TWIK RELATED K+ CHANNELS) CHANNEL FUNCTION"
Assay data:26 Active, 26 Activity ≤ 1 µM, 26 Tested
Thallium flux assay from US Patent US20240190824: "INHIBITORS OF TREK (TWIK RELATED K+ CHANNELS) CHANNEL FUNCTION"
Assay data:99 Active, 92 Activity ≤ 1 µM, 99 Tested
hERG Assay from US Patent US20240189287: "PERIPHERALLY RESTRICTED CB1 RECEPTOR BLOCKERS AND USES THEREOF"
Assay data:2 Active, 3 Tested
hERG Kd Inhibition Assay from US Patent US20240246972: "AZAINDOLE ROCK INHIBITORS"
hERG Inhibition Assay from US Patent US20240216357: "POLYCYCLIC COMPOUND AND APPLICATION THEREOF"
Assay data:23 Active, 41 Tested
SummaryCompounds, ActiveRelated BioAssays by DepositorRelated BioAssays by Target
hERG Qpatch Assay from US Patent US20240208953: ""Cyclopenta[c]pyrrol Negative Allosteric Modulators of NR2B""
Assay data:20 Active, 4 Activity ≤ 1 µM, 25 Tested
SummaryCompounds, ActiveCompounds, activity ≤ 1 µMRelated BioAssays by Target
hERG Qpatch Assay Protocol from US Patent US20240199576: "NOVEL CYCLOPENTA[C]PYRROL NEGATIVE ALLOSTERIC MODULATORS OF NR2B"
Assay data:3 Active, 5 Tested
SummaryCompounds, ActiveRelated BioAssays by Target
[3H]DA and [3H]5-HT Uptake Assay from US Patent US11999676: "Vesicular monoamine transporter-2 ligands and their use in the treatment of psychostimulant abuse"
Assay data:90 Active, 90 Activity ≤ 1 µM, 91 Tested
SummaryCompounds, ActiveCompounds, activity ≤ 1 µMRelated BioAssays by DepositorRelated BioAssays by Target
hERG Channel Inhibitory Activity Assay from US Patent US20240150370: "BICYCLIC PYRIDINE DERIVATIVE"
Assay data:2 Active, 39 Tested
hERG Assay from US Patent US11970463: "Compounds and their use"
Assay data:1 Active, 35 Tested
In Vitro Assay from US Patent US20240101531: "PYRIDINAMINE DERIVATIVES AND THEIR USE AS POTASSIUM CHANNEL MODULATORS"
Assay data:373 Active, 166 Activity ≤ 1 µM, 419 Tested
hERG Channel Activity from US Patent US11912693: "Compounds for modulating S1P1 activity and methods of using the same"
Assay data:1 Active, 1 Activity ≤ 1 µM, 11 Tested
Experimental Evaluation of the In Vitro Inhibitory Effect (IC50) of hERG from US Patent US11912663: "Multi-targeted tyrosine kinase inhibitors and their pharmaceutical uses"
Assay data:15 Tested
Cross screening panel
Assay data:1 Tested
SummaryRelated BioAssays by Target
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