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Selectivity interaction (GPCR panel (PDSP screen)) EUB0001492b HTR1D
Assay data:1 Tested
SummaryRelated BioAssays by Target
Selectivity interaction (CEREB panel (panel of receptors, transporters, ion channels, and other enzymes)) EUB0001119a HTR1B
Selectivity interaction (GPCR panel (PDSP screen)) EUB0001079a HTR1D
Selectivity interaction (GPCR panel (PDSP screen)) EUB0001079a HTR1B
Selectivity interaction (Panel of non-epigenetic targets (kinases, GPCRs, ion channels, and transporters, Eurofins) ) EUB0000271b HTR1B
Selectivity interaction (GPCR panel (PDSP screen)) EUB0001072a HTR1D
Selectivity interaction (GPCR panel (PDSP screen)) EUB0001072a HTR1B
Selectivity interaction (GPCR panel (PDSP screen)) EUB0000276b HTR1D
Selectivity interaction (GPCR panel (PDSP screen)) EUB0000276b HTR1B
Selectivity interaction (Panel of kinases, GPCRs, ion channels and transporters (enzymatic assay)) EUB0000223bCl HTR1B
Selectivity interaction (Panel of kinases, GPCRs, ion channels and transporters (enzymatic assay)) EUB0000266bCl HTR1B
Selectivity interaction (Safety Panel 44tm (Eurofins)) EUB0000162b HTR1B
Selectivity interaction (BET inhibitor selectivity panel (Human antagonist GTPgS assay)) EUB0000102c HTR1B
Activity against 5HT1/R in the Eurofins Panlabs screen (BI) by Radioactive Assay
Inhibitor of 5HT1B/R in the Eurofins SafetyScreen44 (BI) by Radioactive Assay (Old_Cerep_1)
Agonist activity in the Eurofins SafetyScreen44 (CEREP) (BI) against 5HT1B(H) by Scintillation counting (Cerep_4376)
Assay data:4 Tested
SafetyScreen: 5-HT1B Human Serotonin GPCR Binding Antagonist Radioligand LeadHunter Assay, catalogue number: 4376
Assay data:10 Tested
PDSP Primary Binding target: HTR1D - Compounds are tested at 10 uM concentration, plate are incubated at room temperature in the dark for 90 minutes. Reaction are stopped by vacuum filtration onto 0.3% polyethyleneimine soaked filter mats using Filtermate harvester. Scintilation cocktail is then melted onto microwave-dried filters on a hot plate and the radio activity is counted in Microbia counter.
Assay data:48 Active, 167 Tested
SummaryCompounds, ActiveRelated BioAssays by Target
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