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Substrate uptake and inhibition of the Na(+)/L-Ascorbic Acid Transporter 1 (SVCT1, SLC23A1) as assessed by the fluorescent FLIPR membrane potential dye in HEK-293 JumpIN-SLC23A1 cells (PubChem AID: 1794810)
Assay data:2 Tested
SummaryRelated BioAssays by Target
Membrane potential based assay for SLC23A1 using HEK-293 SLC23A1 OE cells
Assay data:1 Active, 2 Tested
SummaryCompounds, ActiveRelated BioAssays by DepositorRelated BioAssays by Target
Human Sodium-dependent vitamin C transporter 1 (SLC23 family of ascorbic acid transporters)
Assay data:2 Active, 2 Tested
SummaryCompounds, ActivePubMed CitationRelated BioAssays by Target
[14C]- AA uptake mediated by sodium-dependent ascorbate transporters, SVCT2 measured as maximum velocity (Vmax) at a concentration of 750 nM
Assay data:1 Tested
SummaryPubMed CitationRelated BioAssays by Target
[14C]- AA uptake mediated by sodium-dependent ascorbate transporters, SVCT2 measured as maximum velocity (Vmax) at a concentration of 500 uM
[14C]- AA uptake mediated by sodium-dependent ascorbate transporters, SVCT2 measured as maximum velocity (Vmax) at a concentration of 3 uM
[14C]- AA uptake mediated by sodium-dependent ascorbate transporters, SVCT2 measured as maximum velocity (Vmax) at a concentration of 250 nM
[14C]- AA uptake mediated by sodium-dependent ascorbate transporters, SVCT2 measured as maximum velocity (Vmax) at a concentration of 100 uM
Uptake of ([14C]- AA) mediated by sodium-dependent ascorbate transporters, SVCT2 measured as Maximum velocity (Vmax) at concentration of 5 uM
Uptake of ([14C]- AA) mediated by sodium-dependent ascorbate transporters, SVCT2 measured as Maximum velocity (Vmax)
[14C]- AA uptake mediated by sodium-dependent ascorbate transporters, SVCT2 measured as maximum velocity (Vmax) at a concentration of 5 mM
[14C]- AA uptake mediated by sodium-dependent ascorbate transporters, SVCT2 measured as maximum velocity (Vmax) at a concentration of 2 mM
([14C]- AA) and its uptake mediated by sodium-dependent ascorbate transporters, SVCT2 measured as Maximum velocity (Vmax) at concentration of 60 uM
([14C]- AA) and its uptake mediated by sodium-dependent ascorbate transporters, SVCT2 measured as Maximum velocity (Vmax) at concentration of 6 uM
([14C]- AA) and its uptake mediated by sodium-dependent ascorbate transporters, SVCT2 measured as Maximum velocity (Vmax) at concentration of 24 uM
([14C]- AA) and its uptake mediated by sodium-dependent ascorbate transporters, SVCT2 measured as Maximum velocity (Vmax) at concentration of 120 uM
([14C]- AA) and its uptake mediated by sodium-dependent ascorbate transporters, SVCT2 measured as Maximum velocity (Vmax) at concentration of 12 uM
[14C]- AA uptake mediated by sodium-dependent ascorbate transporters, SVCT2 measured as Michaelis-Menten constant (Kt) at a concentration of 24 uM
[14C]- AA uptake mediated by sodium-dependent ascorbate transporters, SVCT2 measured as Michaelis-Menten constant (Kt) at a concentration of 750 nM
[14C]- AA uptake mediated by sodium-dependent ascorbate transporters, SVCT2 measured as Michaelis-Menten constant (Kt) at a concentration of 60 uM
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