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Safety47 Scan (DiscoverX - Eurofins)
Assay data:1 Tested
SummaryRelated BioAssays by Target
Adrenergic alpha2A Eurofins Panlabs panel
ALPHA2A/HU Eurofins SafetyScreen44 (BI)
Binding affinity towards human ADRA2A in an in vitro assay with cellular components measured by scintillation counting
Assay data:24 Active, 17 Activity ≤ 1 µM, 40 Tested
SummaryCompounds, ActiveCompounds, activity ≤ 1 µMPubMed CitationRelated BioAssays by Target
Assay data:1 Active, 1 Tested
SummaryCompounds, ActivePubMed CitationRelated BioAssays by Target
Assay data:63 Active, 20 Activity ≤ 1 µM, 323 Tested
Assay data:129 Active, 50 Activity ≤ 1 µM, 927 Tested
Antagonist activity at human ADRA2A in an in vitro cell-based assay measured by fluorescent imaging plate reader
Assay data:80 Active, 18 Activity ≤ 1 µM, 1172 Tested
Agonist activity at human ADRA2A in an in vitro cell-based assay measured by fluorescent imaging plate reader
Assay data:24 Active, 11 Activity ≤ 1 µM, 1195 Tested
Displacement of [3H]-RX 821002 from rat alpha2 adrenoceptor at 10 uM after 60 mins by scintillation counting analysis relative to control
Assay data:3 Tested
SummaryPubMed CitationRelated BioAssays by Target
Agonist activity at human adrenergic receptor expressed in CHO cells
Assay data:2 Active, 1 Activity ≤ 1 µM, 2 Tested
Agonist activity at human adrenergic receptor expressed in CHO cells assessed as intrinsic activity
Assay data:2 Tested
Antagonist activity at alpha2a-adrenoceptor (unknown origin) assessed as reduction in adrenaline-induced response by measuring equilibrium binding constant
Assay data:12 Active, 12 Activity ≤ 1 µM, 12 Tested
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