Related BioAssays, by Target Similarity (List) for PubChem BioAssay (S - PubChem BioAssay - NCBI

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Select item 19630451.

Safety47 Scan (DiscoverX - Eurofins)

Source:: ChEMBL

Protein Target:: 5-hydroxytryptamine receptor 1A

Assay data:1 Tested

AID:: 1963045

Summary Related BioAssays by Target

Select item 19630442.

Safety47 Scan (DiscoverX - Eurofins)

Source:: ChEMBL

Protein Target:: 5-hydroxytryptamine receptor 1A

Assay data:1 Tested

AID:: 1963044

Summary Related BioAssays by Target

Select item 19625513.

Serotonin (5-Hydroxytryptamine) 5-HT1A Eurofins Panlabs panel

Source:: ChEMBL

Protein Target:: 5-hydroxytryptamine receptor 1A

Assay data:1 Tested

AID:: 1962551

Summary Related BioAssays by Target

Select item 19623614.

5HT1A/H Eurofins SafetyScreen44 (BI)

Source:: ChEMBL

Protein Target:: 5-hydroxytryptamine receptor 1A

Assay data:1 Tested

AID:: 1962361

Summary Related BioAssays by Target

Select item 19623125.

5HT1A/H Eurofins SafetyScreen44 (BI)

Source:: ChEMBL

Protein Target:: 5-hydroxytryptamine receptor 1A

Assay data:1 Tested

AID:: 1962312

Summary Related BioAssays by Target

Select item 19622116.

5HT1A/H Eurofins SafetyScreen44 (BI)

Source:: ChEMBL

Protein Target:: 5-hydroxytryptamine receptor 1A

Assay data:1 Tested

AID:: 1962211

Summary Related BioAssays by Target

Select item 19621677.

5HT1A/H Eurofins SafetyScreen44 (BI)

Source:: ChEMBL

Protein Target:: 5-hydroxytryptamine receptor 1A

Assay data:1 Tested

AID:: 1962167

Summary Related BioAssays by Target

Select item 19621538.

5HT1A/H Eurofins SafetyScreen44 (BI)

Source:: ChEMBL

Protein Target:: 5-hydroxytryptamine receptor 1A

Assay data:1 Tested

AID:: 1962153

Summary Related BioAssays by Target

Select item 19620719.

5HT1A/H Eurofins SafetyScreen44 (BI)

Source:: ChEMBL

Protein Target:: 5-hydroxytryptamine receptor 1A

Assay data:1 Tested

AID:: 1962071

Summary Related BioAssays by Target

Select item 196202710.

5HT1A/H Eurofins SafetyScreen44 (BI)

Source:: ChEMBL

Protein Target:: 5-hydroxytryptamine receptor 1A

Assay data:1 Tested

AID:: 1962027

Summary Related BioAssays by Target

Select item 196187311.

Binding affinity towards human HTR1A in an in vitro assay with cellular components measured by scintillation counting

Source:: ChEMBL

Protein Target:: 5-hydroxytryptamine receptor 1A

Assay data:7 Active, 7 Activity ≤ 1 µM, 21 Tested

AID:: 1961873

Summary Compounds, Active Compounds, activity ≤ 1 µM PubMed Citation Related BioAssays by Target

Select item 196185312.

Binding affinity towards human HTR1A in an in vitro assay with cellular components measured by scintillation counting

Source:: ChEMBL

Protein Target:: 5-hydroxytryptamine receptor 1A

Assay data:56 Active, 33 Activity ≤ 1 µM, 377 Tested

AID:: 1961853

Summary Compounds, Active Compounds, activity ≤ 1 µM PubMed Citation Related BioAssays by Target

Select item 196177213.

Binding affinity towards human HTR1A in an in vitro assay with cellular components measured by scintillation counting

Source:: ChEMBL

Protein Target:: 5-hydroxytryptamine receptor 1A

Assay data:141 Active, 68 Activity ≤ 1 µM, 927 Tested

AID:: 1961772

Summary Compounds, Active Compounds, activity ≤ 1 µM PubMed Citation Related BioAssays by Target

Select item 196177114.

Antagonist activity at human HTR1A in an in vitro cell-based assay measured by fluorescent imaging plate reader

Source:: ChEMBL

Protein Target:: 5-hydroxytryptamine receptor 1A

Assay data:58 Active, 20 Activity ≤ 1 µM, 876 Tested

AID:: 1961771

Summary Compounds, Active Compounds, activity ≤ 1 µM PubMed Citation Related BioAssays by Target

Select item 196177015.

Agonist activity at human HTR1A in an in vitro cell-based assay measured by fluorescent imaging plate reader

Source:: ChEMBL

Protein Target:: 5-hydroxytryptamine receptor 1A

Assay data:41 Active, 16 Activity ≤ 1 µM, 1178 Tested

AID:: 1961770

Summary Compounds, Active Compounds, activity ≤ 1 µM PubMed Citation Related BioAssays by Target

Select item 195840916.

Displacement of [3H]8-OH-DPAT from recombinant human 5-HT1A receptor at 10 uM after 60 mins by scintillation counting analysis relative to control

Source:: ChEMBL

Protein Target:: 5-hydroxytryptamine receptor 1A

Assay data:3 Tested

AID:: 1958409

Summary PubMed Citation Related BioAssays by Target

Select item 195251817.

Displacement of [3H]-8-OH-DPAT from human 5-HT1A receptor expressed in HEK cell membrane incubated for 120 mins by microplate beta scintillation counting analysis

Source:: ChEMBL

Protein Target:: 5-hydroxytryptamine receptor 1A

Assay data:14 Active, 1 Activity ≤ 1 nM, 5 Activity ≤ 1 µM, 14 Tested

AID:: 1952518

Summary Compounds, Active Compounds, activity ≤ 1 µM PubMed Citation Related BioAssays by Target

Select item 195251718.

Displacement of [3H]-8-OH-DPAT from human 5-HT1A receptor expressed in HEK cell membrane at 10 uM incubated for 120 mins by microplate beta scintillation counting analysis

Source:: ChEMBL

Protein Target:: 5-hydroxytryptamine receptor 1A

Assay data:5 Tested

AID:: 1952517

Summary PubMed Citation Related BioAssays by Target

Select item 194345119.

Agonist activity at rat hippocampal 5-HT1AR

Source:: ChEMBL

Protein Target:: 5-hydroxytryptamine receptor 1A

Assay data:1 Active, 1 Activity ≤ 1 µM, 1 Tested

AID:: 1943451

Summary Compounds, Active Compounds, activity ≤ 1 µM PubMed Citation Related BioAssays by Target

Select item 194345020.

Binding affinity to human 5-HT1AR transfected in HEK293 cells assessed as inhibition constant

Source:: ChEMBL

Protein Target:: 5-hydroxytryptamine receptor 1A

Assay data:1 Active, 1 Activity ≤ 1 µM, 1 Tested

AID:: 1943450

Summary Compounds, Active Compounds, activity ≤ 1 µM PubMed Citation Related BioAssays by Target

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Target

Proteins (31)
BioAssays with protein sequences specified as targets

BioActivity

Active Compounds (1,420)
BioAssays with compounds reported as biologically active
Activity (IC50, etc) ≤ 1 nM (372)
BioAssays with the active concentration of tested reagents less than 1 nanomolar
Activity (IC50, etc) ≤ 1 µM (1,311)
BioAssays with the active concentration of tested reagents less than 1 micromolar

Experiment Type

Confirmatory (1,486)
Low-throughput BioAssays where the activity outcome is based on a dose-response relationship with multiple tested concentrations
Primary Screening (7)
Primary high-throughput BioAssays where the activity outcome is based on percentage inhibition from a single dose

Assay Project (24)
BioAssays organized into assay projects based on linkage to Summary assays. Click an project below to retrieve the bioassay list for the project. Click 'All Assay Projects' to retrieve all assay projects represented by Summary assays.

Depositor Category

Literature Extraction (2,353)
BioAssays extracted from the literature
NIH MLP (27)
BioAssays deposited by the NIH Molecular Libraries Program
Other (63)
BioAssays deposited by other experimentalists

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