Related BioAssays, by Target Similarity (List) for PubChem BioAssay (S - PubChem BioAssay - NCBI

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Select item 19637051.

CDK Inhibition In Vitro Assay from US Patent US20240150369: "CYCLIN-DEPENDENT KINASE INHIBITING COMPOUNDS FOR THE TREATMENT OF MEDICAL DISORDERS"

Source:: BindingDB

Protein Targets:: Cyclin-A2; ...
Total:: 16

Assay data:31 Active, 8 Activity ≤ 1 nM, 31 Activity ≤ 1 µM, 31 Tested

AID:: 1963705

Summary Compounds, Active Compounds, activity ≤ 1 µM Related BioAssays by Target

Select item 19583582.

Inhibition of CDK5/p25 (unknown origin) at 1 uM relative to control

Source:: ChEMBL

Protein Targets:: Cyclin-dependent kinase 5 activator 1; ...
Total:: 2

Assay data:3 Tested

AID:: 1958358

Summary PubMed Citation Related BioAssays by Target

Select item 19498083.

Inhibition of CDK5 (unknown origin)

Source:: ChEMBL

Protein Target:: Cyclin-dependent-like kinase 5

Assay data:1 Active, 1 Activity ≤ 1 nM, 1 Activity ≤ 1 µM, 1 Tested

AID:: 1949808

Summary Compounds, Active Compounds, activity ≤ 1 µM PubMed Citation Related BioAssays by Target

Select item 19490374.

Inhibition of CDK5/p25 (unknown origin) by Ambit kinase assay

Source:: ChEMBL

Protein Targets:: Cyclin-dependent kinase 5 activator 1; ...
Total:: 2

Assay data:4 Tested

AID:: 1949037

Summary PubMed Citation Related BioAssays by Target

Select item 19483305.

Inhibition of CDK5 (unknown origin)

Source:: ChEMBL

Protein Target:: Cyclin-dependent-like kinase 5

Assay data:1 Active, 1 Tested

AID:: 1948330

Summary Compounds, Active PubMed Citation Related BioAssays by Target

Select item 19476766.

Inhibition of recombinant human CDK5/p25 expressed in Sf9 insect cells incubated for 60 mins in presence of ATP and [gamma33-P] ATP by radiometric scintillation counter analysis

Source:: ChEMBL

Protein Targets:: Cyclin-dependent kinase 5 activator 1; ...
Total:: 2

Assay data:16 Active, 9 Activity ≤ 1 µM, 56 Tested

AID:: 1947676

Summary Compounds, Active Compounds, activity ≤ 1 µM PubMed Citation Related BioAssays by Target

Select item 19470607.

Inhibition of CDK5 (unknown origin)

Source:: ChEMBL

Protein Target:: Cyclin-dependent-like kinase 5

Assay data:1 Active, 1 Activity ≤ 1 nM, 1 Activity ≤ 1 µM, 1 Tested

AID:: 1947060

Summary Compounds, Active Compounds, activity ≤ 1 µM PubMed Citation Related BioAssays by Target

Select item 19405738.

Inhibition of CDK5/p25 (unknown origin) at 1 uM incubated for 30 to 60 mins presence of dithiothreitol by Cheng-Prusoff equation analysis relative to control

Source:: ChEMBL

Protein Targets:: Cyclin-dependent kinase 5 activator 1; ...
Total:: 2

Assay data:11 Tested

AID:: 1940573

Summary PubMed Citation Related BioAssays by Target

Select item 19405729.

Inhibition of CDK5/p25 (unknown origin) assessed as inhibition constant incubated for 30 to 60 mins presence of dithiothreitol by Cheng-Prusoff equation analysis

Source:: ChEMBL

Protein Targets:: Cyclin-dependent kinase 5 activator 1; ...
Total:: 2

Assay data:9 Active, 9 Activity ≤ 1 µM, 10 Tested

AID:: 1940572

Summary Compounds, Active Compounds, activity ≤ 1 µM PubMed Citation Related BioAssays by Target

Select item 194028110.

Inhibition of CDK5/p25 (unknown origin)

Source:: ChEMBL

Protein Targets:: Cyclin-dependent kinase 5 activator 1; ...
Total:: 2

Assay data:1 Active, 1 Activity ≤ 1 µM, 1 Tested

AID:: 1940281

Summary Compounds, Active Compounds, activity ≤ 1 µM PubMed Citation Related BioAssays by Target

Select item 193880311.

Inhibition of human CDK5/p25 nck5a

Source:: ChEMBL

Protein Targets:: Cyclin-dependent kinase 5 activator 1; ...
Total:: 2

Assay data:1 Active, 2 Tested

AID:: 1938803

Summary Compounds, Active PubMed Citation Related BioAssays by Target

Select item 193482512.

Inhibition of CDK5 (unknown origin)

Source:: ChEMBL

Protein Target:: Cyclin-dependent-like kinase 5

Assay data:1 Tested

AID:: 1934825

Summary PubMed Citation Related BioAssays by Target

Select item 193482413.

Inhibition of CDK3 (unknown origin)

Source:: ChEMBL

Protein Target:: Cyclin-dependent kinase 3

Assay data:1 Active, 1 Tested

AID:: 1934824

Summary Compounds, Active PubMed Citation Related BioAssays by Target

Select item 193225914.

Inhibition of CDK5 (unknown origin)

Source:: ChEMBL

Protein Target:: Cyclin-dependent-like kinase 5

Assay data:2 Active, 2 Tested

AID:: 1932259

Summary Compounds, Active PubMed Citation Related BioAssays by Target

Select item 192753715.

Inhibition of CDK5 (unknown origin)

Source:: ChEMBL

Protein Target:: Cyclin-dependent-like kinase 5

Assay data:3 Active, 1 Activity ≤ 1 nM, 3 Activity ≤ 1 µM, 3 Tested

AID:: 1927537

Summary Compounds, Active Compounds, activity ≤ 1 µM PubMed Citation Related BioAssays by Target

Select item 192548916.

Inhibition of CDK (unknown origin)

Source:: ChEMBL

Protein Targets:: Cyclin-dependent kinase 1; ...
Total:: 20

Assay data:1 Tested

AID:: 1925489

Summary PubMed Citation Related BioAssays by Target

Select item 192434717.

Inhibition of CDK5/p25 (unknown origin)

Source:: ChEMBL

Protein Targets:: Cyclin-dependent kinase 5 activator 1; ...
Total:: 2

Assay data:23 Active, 17 Activity ≤ 1 µM, 25 Tested

AID:: 1924347

Summary Compounds, Active Compounds, activity ≤ 1 µM PubMed Citation Related BioAssays by Target

Select item 192433718.

Inhibition of CDK3/Cyclin E (unknown origin)

Source:: ChEMBL

Protein Targets:: Cyclin-dependent kinase 3; ...
Total:: 2

Assay data:1 Active, 1 Activity ≤ 1 µM, 1 Tested

AID:: 1924337

Summary Compounds, Active Compounds, activity ≤ 1 µM PubMed Citation Related BioAssays by Target

Select item 192150819.

Inhibition of CDK5/p35 (unknown origin)

Source:: ChEMBL

Protein Targets:: Cyclin-dependent kinase 5 activator 1; ...
Total:: 2

Assay data:2 Active, 2 Activity ≤ 1 µM, 2 Tested

AID:: 1921508

Summary Compounds, Active Compounds, activity ≤ 1 µM PubMed Citation Related BioAssays by Target

Select item 192149320.

Inhibition of CDK5 (unknown origin) incubated for 120 mins in presence of ATP by HotSpot kinase assay

Source:: ChEMBL

Protein Target:: Cyclin-dependent-like kinase 5

Assay data:2 Tested

AID:: 1921493

Summary PubMed Citation Related BioAssays by Target

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Proteins (17)
BioAssays with protein sequences specified as targets

BioActivity

Chemical Probes (1)
BioAssays with compounds reported as validated chemical probes

Active Compounds (373)
BioAssays with compounds reported as biologically active
Activity (IC50, etc) ≤ 1 nM (35)
BioAssays with the active concentration of tested reagents less than 1 nanomolar
Activity (IC50, etc) ≤ 1 µM (287)
BioAssays with the active concentration of tested reagents less than 1 micromolar

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Summary (1)
BioAssays summarizing information from multiple assays for validated chemical probes or small molecule leads
Confirmatory (413)
Low-throughput BioAssays where the activity outcome is based on a dose-response relationship with multiple tested concentrations
Primary Screening (1)
Primary high-throughput BioAssays where the activity outcome is based on percentage inhibition from a single dose

Assay Project (10)
BioAssays organized into assay projects based on linkage to Summary assays. Click an project below to retrieve the bioassay list for the project. Click 'All Assay Projects' to retrieve all assay projects represented by Summary assays.

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Literature Extraction (894)
BioAssays extracted from the literature
NIH MLP (11)
BioAssays deposited by the NIH Molecular Libraries Program
Other (83)
BioAssays deposited by other experimentalists

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