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MARK4 SGC Tm panel (DSF)
Assay data:1 Tested
SummaryRelated BioAssays by Target
MARK3 SGC Tm panel (DSF)
Inhibition of MARK1 (unknown origin) by Ambit kinase assay
SummaryPubMed CitationRelated BioAssays by Target
Inhibition of MARK2 (unknown origin) by Ambit kinase assay
Inhibition of MARK3 (unknown origin) by Ambit kinase assay
Inhibition of MARK4 (unknown origin) by Ambit kinase assay
Binding affinity to recombinant MARK4 (unknown origin) assessed as dissociation constant by DSF assay
Assay data:1 Active, 1 Activity ≤ 1 nM, 1 Activity ≤ 1 µM, 1 Tested
SummaryCompounds, ActiveCompounds, activity ≤ 1 µMPubMed CitationRelated BioAssays by Target
Binding affinity to recombinant MARK3 (unknown origin) assessed as dissociation constant by DSF assay
Inhibition of recombinant MARK4 (unknown origin) at 10 uM by DSF assay relative to staurosporine
Inhibition of recombinant MARK3 (unknown origin) at 10 uM by DSF assay relative to staurosporine
Binding affinity to recombinant MARK4 (unknown origin) assessed as change in melting temperature at 10 uM by DSF assay
Binding affinity to recombinant MARK3 (unknown origin) assessed as change in melting temperature at 10 uM by DSF assay
Inhibition of MARK3 (unknown origin) at 10 uM relative to control
Selectivity interaction (KinomeScan (DiscoverX)) EUB0000315b MARK3
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