Warning: The NCBI web site requires JavaScript to function. more...
An official website of the United States government
The .gov means it's official. Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you're on a federal government site.
The site is secure. The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.
HIV RT Filter Binding IC50 Assay from US Patent US20240226130: "4'-THIONUCLEOSIDE ANALOGUES AND THEIR PHARMACEUTICAL USE"
Assay data:1 Active, 1 Activity ≤ 1 µM, 1 Tested
SummaryCompounds, ActiveCompounds, activity ≤ 1 µMRelated BioAssays by Target
Inhibition of HIV-1 reverse transcriptase
Assay data:1 Active, 1 Tested
SummaryCompounds, ActivePubMed CitationRelated BioAssays by Target
Inhibition of HIV-1 reverse transcriptase relative to control
Assay data:1 Tested
SummaryPubMed CitationRelated BioAssays by Target
Inhibition of HIV1 reverse transcriptase
Assay data:2 Active, 2 Activity ≤ 1 µM, 9 Tested
SummaryCompounds, ActiveCompounds, activity ≤ 1 µMPubMed CitationRelated BioAssays by Target
Time dependent inhibition of recombinant wildtype HIV-1 reverse transcriptase at 0.1 to 1000000 nM
Assay data:3 Tested
Inhibition of recombinant wildtype HIV-1 reverse transcriptase using r(A)350 as template and d(T)16 as primer preincubated with compound for 1 hrs followed by template/primer addition and measured after 30 mins by picogreen based plate reader analysis
Assay data:7 Active, 7 Activity ≤ 1 µM, 13 Tested
Inhibition of HIV-1 reverse transcriptase incubated for 90 mins by liquid scintillation counting analysis
Assay data:1 Active, 1 Activity ≤ 1 nM, 1 Activity ≤ 1 µM, 1 Tested
Inhibition of wild type recombinant HIV-1 reverse transcriptase using biotin-labelled dNTPs as substrate assessed as inhibition of biotin-labelled UTP incorporation incubated for 1 hr by ELISA
Assay data:5 Active, 5 Activity ≤ 1 µM, 5 Tested
Binding affinity to HIV-1 reverse transcriptase assessed as dissociation constant by SPR analysis
Assay data:2 Active, 2 Tested
Inhibition of HIV1 Reverse transcriptase at 25 uM relative to control
Jurkat Latency Reversal Assay from US Patent US11492361: "Compounds useful in HIV therapy"
Assay data:59 Active, 59 Activity ≤ 1 µM, 59 Tested
Inhibition of recombinant p66/p51 HIV-1 RNase H using 6-FAM-labeld DNA substrate preincubated for 2 mins by fluorescence based assay
Inhibition of HIV-1 reverse transcriptase RNA-dependent DNA polymerase activity assessed as reduction in biotin-dUTP incorporation at 500 nM using poly(A)/oligo (dT)15 as template/primer by ELISA relative to control
Inhibition of HIV-1 reverse transcriptase RNA-dependent DNA polymerase activity assessed as reduction in biotin-dUTP incorporation at 100 nM using poly(A)/oligo (dT)15 as template/primer by ELISA relative to control
Inhibition of HIV1 reverse transcriptase assessed as inhibition of biotin-dUTP incorporation
Assay data:4 Active, 4 Activity ≤ 1 µM, 4 Tested
Inhibition of recombinant wild-type p66/p51 HIV-1 reverse transcriptase incubated for 40 mins by picogreen dye-based spectrofluorometric analysis
Assay data:32 Active, 19 Activity ≤ 1 µM, 40 Tested
Inhibition of wild type HIV-1 reverse transcriptase assessed as reduction of biotin-dUTP incorporation into protein using ABTS as substrate incubated for 1 hrs by ELISA analysis
Inhibition of wild type HIV-1 reverse transcriptase assessed as reduction in luciferase reporter activity by single-round assay
Assay data:3 Active, 2 Activity ≤ 1 nM, 3 Activity ≤ 1 µM, 3 Tested
Inhibition of HIV-1 reverse transcriptase using oligo(dT)16 as primer measured after 40 mins by picogreen-dye based spectrofluorometric analysis
Assay data:34 Active, 34 Activity ≤ 1 µM, 34 Tested
Potency index, ratio of test compound IC50 to NBD-14189 IC50 for inhibition of recombinant HIV-1 reverse transcriptase incubated for 2 hrs by colorimetric assay
Assay data:15 Tested
Filters: Manage Filters
Your browsing activity is empty.
Activity recording is turned off.
Turn recording back on