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Inhibition of TRKC (unknown origin) using TK as substrate in presence of ATP incubated for 40 mins by HTRF KinEASE assay
Assay data:4 Active, 1 Activity ≤ 1 nM, 4 Activity ≤ 1 µM, 4 Tested
SummaryCompounds, ActiveCompounds, activity ≤ 1 µMPubMed CitationRelated BioAssays by Target
Inhibition of TRKC (unknown origin) at 1 uM relative to control
Assay data:1 Tested
SummaryPubMed CitationRelated BioAssays by Target
Inhibition of TRKC (unknown origin) in presence of 50 uM ATP
Assay data:3 Active, 3 Activity ≤ 1 µM, 3 Tested
Inhibition of TRKC (unknown origin)
Assay data:1 Active, 1 Activity ≤ 1 µM, 1 Tested
Selectivity interaction (KinomeScan (DiscoverX, competition-binding assay))
SummaryCompounds, ActiveCompounds, activity ≤ 1 µMRelated BioAssays by Target
Selectivity interaction (KinomeScan (DiscoverX)) EUB0000341aCl NTRK3
SummaryRelated BioAssays by Target
Selectivity interaction (KinomeScan (DiscoverX)) EUB0000294b NTRK3
Selectivity interaction (KinomeScan (Invitrogen)) EUB0000714a NTRK3
Selectivity interaction (Z?-LYTE assay (SelectScreen Invitrogen)) EUB0000690a NTRK3
Selectivity interaction (KinomeScan (DiscoverX)) EUB0000147b NTRK3
Selectivity interaction (Ambit kinome screening platform (Ambit phage-based competition binding assay)) EUB0000624a NTRK3
Affinity Biochemical interaction (Radiometric assay (10 M ATP, Reaction Biology)) EUB0000156b NTRK3
Assay data:1 Active, 1 Tested
SummaryCompounds, ActiveRelated BioAssays by Target
Affinity Biochemical interaction (Radiometric assay (10 M ATP, Reaction Biology)) EUB0000005b NTRK3
Affinity Biochemical interaction (LanthaScreenTM Eu) EUB0000640a NTRK3
Affinity On-target Cellular interaction (Flow cytometry for ETV6-TRKC (inhibition of ERK phosphorylation in NIH 3T3 cells)) EUB0000640a NTRK3
Affinity Phenotypic Cellular interaction (Cell proliferation assay in TRK fusion?containing KM12 cells) EUB0000640a NTRK3
Inhibition of TRKC (unknown origin) using Ser/Thr 06 peptide as substrate incubated for 1 hr in presence of 50 uM ATP by FRET based Z'-Lyte assay
Assay data:10 Active, 10 Activity ≤ 1 µM, 10 Tested
Inhibition of NTRK3 (TRKC) (unknown origin) at 0.1 uM relative to control
Assay data:2 Tested
Inhibition of NTRK3 (TRKC) (unknown origin) at 1 uM relative to control
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