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HSD2 Activity from US Patent US20240209019: "COMPOUNDS AND METHODS FOR TREATING HYPERKALEMIA"
Assay data:38 Active, 29 Activity ≤ 1 µM, 47 Tested
SummaryCompounds, ActiveCompounds, activity ≤ 1 µMRelated BioAssays by Target
Inhibition of human 11beta-HSD1
Assay data:4 Active, 3 Activity ≤ 1 nM, 4 Activity ≤ 1 µM, 4 Tested
SummaryCompounds, ActiveCompounds, activity ≤ 1 µMPubMed CitationRelated BioAssays by Target
Inhibition of human 11beta-HSD2 incubated for 2 hrs by HPLC analysis
Assay data:1 Tested
SummaryPubMed CitationRelated BioAssays by Target
Inhibition of human 11beta-HSD2 incubated for 2 hrs
Inhibition of mouse 11beta-HSD1 in liver microsome incubated for 24 hrs by LC-MS analysis
Assay data:1 Active, 1 Activity ≤ 1 µM, 1 Tested
Inhibition of human 11beta-HSD1 in liver microsome incubated for 24 hrs by LC-MS analysis
Assay data:1 Active, 1 Activity ≤ 1 nM, 1 Activity ≤ 1 µM, 1 Tested
Inhibition of mouse 11beta-HSD1 expressed in CHO-K1 cells incubated for 3 hrs by HTRF assay
Assay data:2 Active, 1 Activity ≤ 1 µM, 2 Tested
Inhibition of mouse 11beta-HSD1 expressed in 3T3-L1 cells incubated for 24 hrs by HTRF assay
Inhibition of mouse 11beta-HSD1 incubated for 24 hrs by HTRF assay
Inhibition of human 11beta-HSD1 incubated for 24 hrs by HTRF assay
Inhibition of human 11beta-HSD1 expressed in CHO-K1 cells incubated for 24 hrs by HTRF assay
Inhibition of mouse 11beta-HSD1 expressed in CHO-K1 cells incubated for 24 hrs by HTRF assay
Inhibition of mouse 11beta-HSD1 using steroid as substrate incubated for 20 to 30 mins by microplate fluorimeter analysis
Inhibition of human 11beta-HSD1 using steroid as substrate incubated for 20 to 30 mins by microplate fluorimeter analysis
Assay data:4 Active, 3 Activity ≤ 1 µM, 4 Tested
Inhibition of rat 11beta-HSD1
Assay data:2 Active, 2 Activity ≤ 1 µM, 2 Tested
Inhibition of mouse 11beta-HSD1
Assay data:2 Active, 1 Activity ≤ 1 nM, 2 Activity ≤ 1 µM, 2 Tested
Inhibition of human 11beta-HSD1 incubated for 22 hrs by HTRF assay
Assay data:3 Active, 1 Activity ≤ 1 nM, 3 Activity ≤ 1 µM, 3 Tested
Inhibition of rat 11beta-HSD1 in kidney microsomes incubated for 20 mins by HPLC analysis
Inhibition of human 11beta-HSD1 incubated for 2 hrs by HPLC analysis
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