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Summary
hERG Inhibition Assay from US Patent US20240216357: "POLYCYCLIC COMPOUND AND APPLICATION THEREOF"
Assay data:23 Active, 41 Tested
SummaryCompounds, ActiveRelated BioAssays by DepositorRelated BioAssays by Target
hERG Qpatch Assay from US Patent US20240208953: ""Cyclopenta[c]pyrrol Negative Allosteric Modulators of NR2B""
Assay data:20 Active, 4 Activity ≤ 1 µM, 25 Tested
SummaryCompounds, ActiveCompounds, activity ≤ 1 µMRelated BioAssays by Target
hERG Qpatch Assay Protocol from US Patent US20240199576: "NOVEL CYCLOPENTA[C]PYRROL NEGATIVE ALLOSTERIC MODULATORS OF NR2B"
Assay data:3 Active, 5 Tested
SummaryCompounds, ActiveRelated BioAssays by Target
[3H]DA and [3H]5-HT Uptake Assay from US Patent US11999676: "Vesicular monoamine transporter-2 ligands and their use in the treatment of psychostimulant abuse"
Assay data:90 Active, 90 Activity ≤ 1 µM, 91 Tested
SummaryCompounds, ActiveCompounds, activity ≤ 1 µMRelated BioAssays by DepositorRelated BioAssays by Target
hERG Channel Inhibitory Activity Assay from US Patent US20240150370: "BICYCLIC PYRIDINE DERIVATIVE"
Assay data:2 Active, 39 Tested
hERG Assay from US Patent US11970463: "Compounds and their use"
Assay data:1 Active, 35 Tested
hERG Channel Activity from US Patent US11912693: "Compounds for modulating S1P1 activity and methods of using the same"
Assay data:1 Active, 1 Activity ≤ 1 µM, 11 Tested
Experimental Evaluation of the In Vitro Inhibitory Effect (IC50) of hERG from US Patent US11912663: "Multi-targeted tyrosine kinase inhibitors and their pharmaceutical uses"
Assay data:15 Tested
SummaryRelated BioAssays by DepositorRelated BioAssays by Target
Cross screening panel
Assay data:1 Tested
SummaryRelated BioAssays by Target
Safety47 Scan (DiscoverX - Eurofins)
Potassium Channel hERG Eurofins Panlabs panel
HERG_DOFETILIDE Eurofins SafetyScreen44 (BI)
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