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Inhibition of mouse Pendrin stably expressed in FRT cells with YFP assessed as inhibition of pendrin mediated Cl-/HCO3- exchange by fluorescence assay
Assay data:1 Active, 1 Tested
SummaryCompounds, ActivePubMed CitationRelated BioAssays by Target
Inhibition of mouse Pendrin stably expressed in FRT cells with YFP assessed as inhibition of pendrin mediated Cl-/NO3- exchange by fluorescence assay
Inhibition of mouse Pendrin stably expressed in FRT cells with YFP assessed as inhibition of pendrin mediated Cl-/SCN- exchange by fluorescence assay
Inhibition of mouse Slc26a4-mediated Cl-/ I- exchange at 10 uM measured by cell-based fluorescence assay
Assay data:1 Tested
SummaryRelated BioAssays by Target
Inhibition of mouse pendrin expressed in FRT cells co-expressing YFP-HIF assessed as reduction in pendrin-mediated kinetics of CI7HCO3(-) exchange by pH-sensitive fluorescent probe BCECF-AM based fluorescence assay relative to control
SummaryCompounds, ActiveRelated BioAssays by Target
Inhibition of mouse pendrin expressed in FRT cells co-expressing YFP-HIF assessed as reduction in pendrin-mediated exchange of Cl(-) with NO3(-) by pH-sensitive fluorescent probe BCECF-AM based fluorescence assay relative to control
Inhibition of mouse pendrin expressed in FRT cells co-expressing YFP-HIF assessed as reduction in pendrin-mediated exchange of Cl(-) with I(-) by pH-sensitive fluorescent probe BCECF-AM based fluorescence assay relative to control
Inhibition of mouse pendrin expressed in FRT cells co-expressing YFP-HIF assessed as reduction in pendrin-mediated exchange of Cl(-) with SCN(-) by pH-sensitive fluorescent probe BCECF-AM based fluorescence assay relative to control
Inhibition of pendrin in human bronchial CFBE assessed as increase in airway surface liquid depth at 25 uM by rhodamine B-dextran fluorescence based confocal microscopy (Rvb = -16 um)
Inhibition of pendrin in human bronchial epithelial cells assessed as increase in airway surface liquid depth at 25 uM by rhodamine B-dextran fluorescence based confocal microscopy (Rvb = -16 um)
Inhibition of pendrin in IL13-stimulated human CFBE assessed as reduction in gluconate gradient-induced intracellular alkalization at 25 uM
Inhibition of pendrin in IL13-stimulated human bronchial epithelial cells assessed as reduction in gluconate gradient-induced intracellular alkalization at 25 uM
Inhibition of human pendrin expressed in FRT cells co-expressing EYFP-HIF assessed as reduction in pendrin-mediated C17HCO3(-) exchange by measuring reduction in cytoplasmic alkalinization exchange at 2.5 uM by pH-sensitive fluorescent probe BCECF-AM based fluorescence assay relative to control
Inhibition of human pendrin expressed in FRT cells co-expressing EYFP-HIF assessed as reduction in pendrin-mediated C17HCO3(-) exchange by measuring reduction in cytoplasmic alkalinization exchange at 25 uM by pH-sensitive fluorescent probe BCECF-AM based fluorescence assay relative to control
Assay data:2 Active, 2 Tested
Time dependent inhibition of human pendrin expressed in FRT cells co-expressing EYFP-HIF assessed as reduction in pendrin-mediated C17SCN(-) exchange by pH-sensitive fluorescent probe BCECF-AM based fluorescence assay relative to control
Assay data:2 Tested
Reversible inhibition of human pendrin expressed in FRT cells co-expressing EYFP-HIF assessed as reduction in pendrin-mediated C17SCN(-) exchange incubated for 10 mins measured after wash out by pH-sensitive fluorescent probe BCECF-AM based fluorescence assay relative to control
Inhibition of human pendrin expressed in FRT cells co-expressing EYFP-HIF assessed as reduction in pendrin-mediated C17NO3(-) exchange incubated for 10 mins by pH-sensitive fluorescent probe BCECF-AM based fluorescence assay relative to control
Inhibition of human pendrin expressed in FRT cells co-expressing EYFP-HIF assessed as reduction in pendrin-mediated Cl(-)/r exchange incubated for 10 mins by pH-sensitive fluorescent probe BCECF-AM based fluorescence assay relative to control
Inhibition of human pendrin expressed in FRT cells co-expressing EYFP-HIF assessed as reduction in pendrin-mediated C17F exchange incubated for 10 mins by pH-sensitive fluorescent probe BCECF-AM based fluorescence assay relative to control
Inhibition of human pendrin expressed in FRT cells co-expressing EYFP-HIF assessed as reduction in pendrin-mediated C17SCN(-) exchange incubated for 10 mins by pH-sensitive fluorescent probe BCECF-AM based fluorescence assay relative to control
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