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Inhibition of ODC in human DU145 cells at 100 uM after 3 days
Assay data:3 Active, 4 Tested
SummaryCompounds, ActivePubMed CitationRelated BioAssays by Target
Inhibition of ODC in human DU145 cells at 100 uM after 6 hrs
Human Ornithine decarboxylase (Decarboxylases)
Assay data:2 Active, 2 Tested
Inhibition of rat liver ornithine decarboxylase
Assay data:1 Active, 1 Tested
Competitive inhibition of Sprague-Dawley rat prostate ornithine decarboxylase using DL-[1-14C]ornithine as substrate by liquid scintillation counting analysis
Assay data:1 Tested
SummaryPubMed CitationRelated BioAssays by Target
Inhibition of rat prostate ornithine decarboxylase at 10 mM
Competitive inhibition of bull prostate ornithine decarboxylase using DL-[1-14C]ornithine as substrate after 1 hr by dixon plot analysis
Assay data:7 Tested
Competitive inhibition of ornithine decarboxylase in rat HTC cells using DL-[1-14C]ornithine as substrate at 1 mM after 1 hr by dixon plot analysis
Competitive inhibition of ornithine decarboxylase in rat HTC cells using DL-[1-14C]ornithine as substrate after 1 hr by dixon plot analysis
Assay data:6 Tested
Competitive inhibition of rat liver ornithine decarboxylase using DL-[1-14C]ornithine as substrate at 0.25 mM after 1 hr by dixon plot analysis
Competitive inhibition of rat liver ornithine decarboxylase using DL-[1-14C]ornithine as substrate at 4 mM after 1 hr by dixon plot analysis
Assay data:2 Tested
Competitive inhibition of rat liver ornithine decarboxylase using DL-[1-14C]ornithine as substrate at 1 mM after 1 hr by dixon plot analysis
Competitive inhibition of rat liver ornithine decarboxylase using DL-[1-14C]ornithine as substrate after 1 hr by dixon plot analysis
Binding affinity to ODC (unknown origin)
Assay data:1 Active, 1 Activity ≤ 1 µM, 7 Tested
SummaryCompounds, ActiveCompounds, activity ≤ 1 µMRelated BioAssays by Target
Inhibition of Rattus norvegicus Wistar (rat) rat liver ODC assessed as inhibition of 14CO2 release from L-[14C]ornithine
SummaryCompounds, ActiveRelated BioAssays by Target
Experimentally measured binding affinity data (Ki) for protein-ligand complexes derived from PDB
Assay data:3598 Active, 421 Activity ≤ 1 nM, 2233 Activity ≤ 1 µM, 3598 Tested
SummaryCompounds, ActiveCompounds, activity ≤ 1 µMPubMed CitationRelated BioAssays by DepositorRelated BioAssays by Target
Activity of ornithine decarboxylase in human DU145 cells assessed per ug DNA at 100 uM after 24 hrs in presence of serum amine oxidase inhibitor aminoguanidine (RVb = 29.3 +/- 1.4 pmol/h per ug DNA)
Assay data:4 Tested
Activity of ornithine decarboxylase in human DU145 cells assessed per ug DNA at 100 uM after 48 hrs in presence of serum amine oxidase inhibitor aminoguanidine (RVb = 17.7+/- 2.6 pmol/h per ug DNA)
Activity of ornithine decarboxylase in human DU145 cells assessed per ug DNA at 100 uM after 72 hrs in presence of serum amine oxidase inhibitor aminoguanidine (RVb = 7.5+/- 0.9 pmol/h per ug DNA)
Assay data:2 Active, 2 Activity ≤ 1 µM, 2 Tested
SummaryCompounds, ActiveCompounds, activity ≤ 1 µMPubMed CitationRelated BioAssays by Target
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